Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50032161
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325178((R)-3-amino-N-(2-chloro-5-(3-methoxypropyl)benzyl)...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325178((R)-3-amino-N-(2-chloro-5-(3-methoxypropyl)benzyl)...)
Affinity DataIC50:  0.0900nMpH: 7.4Assay Description:Inhibition of human recombinant renin in presence of pH 7.4 bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325178((R)-3-amino-N-(2-chloro-5-(3-methoxypropyl)benzyl)...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human recombinant renin in presence of plasma by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325178((R)-3-amino-N-(2-chloro-5-(3-methoxypropyl)benzyl)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of CYP3A4 in human liver microsome preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325178((R)-3-amino-N-(2-chloro-5-(3-methoxypropyl)benzyl)...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed