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Found 36 Enz. Inhib. hit(s) with all data for entry = 50001329
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 assessed as reduction in CO2 hydration preincubated for 10 mins by stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276359(CHEMBL4129303)
Affinity DataIC50:  0.134nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate after 15 mins by amplex red reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276368(CHEMBL4128371)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate after 15 mins by amplex red reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  86nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM193852((E)-3-(2-(2-(1-(4-bromophenyl)ethylidene)hydraziny...)
Affinity DataIC50:  110nMAssay Description:Inhibition of calf lens ALR2 using D,L-glyceraldehyde as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human COX1 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by TLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276360(CHEMBL4126559)
Affinity DataIC50:  310nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM193866(3-(4-((2-Chlorophenylamino)methyl)-5-thioxo-4,5-di...)
Affinity DataIC50:  310nMAssay Description:Inhibition of calf lens ALR2 using D,L-glyceraldehyde as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276310(CHEMBL4127794)
Affinity DataIC50:  310nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276366(CHEMBL4129984)
Affinity DataIC50:  310nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276369(CHEMBL4127948)
Affinity DataIC50:  310nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM193869(3-(4-(Morpholinomethyl)-5-thioxo-4,5-dihydro-1,3,4...)
Affinity DataIC50:  340nMAssay Description:Inhibition of calf lens ALR2 using D,L-glyceraldehyde as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276367(CHEMBL4129191)
Affinity DataIC50:  390nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM193860((E)-3-(2-(2-((2-amino-4-chlorophenyl)(phenyl)methy...)
Affinity DataIC50:  459nMAssay Description:Inhibition of bovine kidney ALR1 using D-glucoronic acid as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276361(CHEMBL4129493)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of calf intestinal alkaline phosphatase using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  2.41E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human COX2 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 45 mins by TL...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Bos taurus)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM193864(3-(4-((Butylamino)methyl)-5-thioxo-4,5-dihydro-1,3...)
Affinity DataIC50:  3.36E+3nMAssay Description:Inhibition of bovine kidney ALR1 using D-glucoronic acid as substrate preincubated for 5 mins followed by NADPH addition measured after 10 mins by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  4.15E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM152478(1-(4-(8-Methoxy-2-oxo-2H-chromen-3-yl)thiazol-2-yl...)
Affinity DataIC50:  4.58E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM152467(1-(4-Fluorophenyl)-3-(4-(6-nitro-2-oxo-2H-chromen-...)
Affinity DataIC50:  4.93E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276371(CHEMBL4128061)
Affinity DataIC50:  5.85E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured at 1 min ti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoxygenase(Glycine max)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276365(CHEMBL4127281)
Affinity DataIC50:  6.25E+3nMAssay Description:Inhibition of soybean lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured at 1 min ti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.68E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  1.74E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoxygenase(Glycine max)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276370(CHEMBL4126039)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of soybean lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoxygenase(Glycine max)
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of soybean lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276371(CHEMBL4128061)
Affinity DataIC50:  3.25E+4nMAssay Description:Inhibition of human plasmatic BuChE using butylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured at 1 min time...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276360(CHEMBL4126559)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human COX1 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by TLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276369(CHEMBL4127948)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human COX1 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by TLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276366(CHEMBL4129984)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human COX1 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by TLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276367(CHEMBL4129191)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human COX1 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by TLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbottabad University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50276310(CHEMBL4127794)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human COX1 using [14C]arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by TLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed