Compile Data Set for Download or QSAR
maximum 50k data
Found 52 Enz. Inhib. hit(s) with all data for entry = 50019421
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204580(CHEMBL247667 | N-phenethyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204580(CHEMBL247667 | N-phenethyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  5nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204587((S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204590((S)-6-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-5...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204590((S)-6-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-5...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204586(6-(3-methoxy-4-(2-(piperidin-1-yl)ethoxy)phenyl)-5...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204582(5-phenyl-N-(2-(piperazin-1-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  9nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204583((S)-(4-ethylpiperazin-1-yl)(4-(5-phenyl-4-((tetrah...)
Affinity DataIC50:  11nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204587((S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204585((S)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)pheny...)
Affinity DataIC50:  11nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204576(6-(4-morpholinophenyl)-5-phenyl-N-(2-(piperazin-1-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204583((S)-(4-ethylpiperazin-1-yl)(4-(5-phenyl-4-((tetrah...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204588(6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-(...)
Affinity DataIC50:  14nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204591(5-phenyl-N-(2-(piperidin-4-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  14nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204585((S)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)pheny...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204576(6-(4-morpholinophenyl)-5-phenyl-N-(2-(piperazin-1-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204592(6-(3-methoxy-4-(2-(piperidin-1-yl)ethoxy)phenyl)-5...)
Affinity DataIC50:  22nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204584((4-(5-phenyl-4-(2-(piperazin-1-yl)ethylamino)furo[...)
Affinity DataIC50:  22nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204589((S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204577(6-(4-(morpholinomethyl)phenyl)-5-phenyl-N-(2-(pipe...)
Affinity DataIC50:  27nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204579(CHEMBL247866 | N-isopropyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  36nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204586(6-(3-methoxy-4-(2-(piperidin-1-yl)ethoxy)phenyl)-5...)
Affinity DataIC50:  38nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204575(6-(4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-y...)
Affinity DataIC50:  42nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204582(5-phenyl-N-(2-(piperazin-1-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  45nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204579(CHEMBL247866 | N-isopropyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  78nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM17714(5,6-diphenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-d...)
Affinity DataIC50:  81nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204578(CHEMBL399008 | N-tert-butyl-5-phenyl-6-(4-(2-(pyrr...)
Affinity DataIC50:  83nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204584((4-(5-phenyl-4-(2-(piperazin-1-yl)ethylamino)furo[...)
Affinity DataIC50:  85nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204577(6-(4-(morpholinomethyl)phenyl)-5-phenyl-N-(2-(pipe...)
Affinity DataIC50:  91nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204575(6-(4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-y...)
Affinity DataIC50:  97nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204582(5-phenyl-N-(2-(piperazin-1-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  98nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204589((S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50:  122nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204588(6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-(...)
Affinity DataIC50:  148nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM17714(5,6-diphenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-d...)
Affinity DataIC50:  181nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204591(5-phenyl-N-(2-(piperidin-4-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  332nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204582(5-phenyl-N-(2-(piperazin-1-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  397nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204581((R)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50:  523nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204579(CHEMBL247866 | N-isopropyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  537nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204592(6-(3-methoxy-4-(2-(piperidin-1-yl)ethoxy)phenyl)-5...)
Affinity DataIC50:  586nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204578(CHEMBL399008 | N-tert-butyl-5-phenyl-6-(4-(2-(pyrr...)
Affinity DataIC50:  650nMAssay Description:Inhibition of Ack1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204579(CHEMBL247866 | N-isopropyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  914nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204582(5-phenyl-N-(2-(piperazin-1-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  960nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204582(5-phenyl-N-(2-(piperazin-1-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  992nMAssay Description:Inhibition of ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204579(CHEMBL247866 | N-isopropyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204581((R)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204579(CHEMBL247866 | N-isopropyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204582(5-phenyl-N-(2-(piperazin-1-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204579(CHEMBL247866 | N-isopropyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  3.27E+3nMAssay Description:Inhibition of ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204579(CHEMBL247866 | N-isopropyl-5-phenyl-6-(4-(2-(pyrro...)
Affinity DataIC50:  4.89E+3nMAssay Description:Inhibition of Jak2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50204582(5-phenyl-N-(2-(piperazin-1-yl)ethyl)-6-(4-(2-(pyrr...)
Affinity DataIC50: >8.33E+3nMAssay Description:Inhibition of Jak2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 52 total ) | Next | Last >>
Jump to: