Affinity DataKi: 0.00545nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0283nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Evaluated for inhibition of thymidylate synthase (TS) from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Compound was tested for inhibition of AICAR formyltransferaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Compound was tested for inhibition of AICAR formyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+4nMAssay Description:Evaluated for inhibition of thymidylate synthase (TS) from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Evaluated for inhibition of thymidylate synthase (TS) from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Evaluated for inhibition of thymidylate synthase (TS) from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+5nMAssay Description:Evaluated for inhibition of thymidylate synthase (TS) from Lactobacillus caseiMore data for this Ligand-Target Pair