Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50013847
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135417(((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  7nMAssay Description:Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135413((5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2,3,4...)
Affinity DataIC50:  7nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135420(((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  8nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135414(Biphenyl-2-carboxylic acid {4-[2-(2-hydroxy-ethyl)...)
Affinity DataIC50:  8nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135419(2-(5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2,3...)
Affinity DataIC50:  12nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135418(3-((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  15nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135415(3-((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  16nMAssay Description:Inhibition of vasopressin induced cAMP accumulation in human V2 receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135423(Biphenyl-2-carboxylic acid {4-[2-(2-tetrazol-1-yl-...)
Affinity DataIC50:  20nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptor at 0.2 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135418(3-((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  30nMAssay Description:Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135420(((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  30nMAssay Description:Inhibition of vasopressin induced cAMP accumulation in human V2 receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135417(((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  36nMAssay Description:Inhibition of vasopressin induced cAMP accumulation in human V2 receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135413((5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2,3,4...)
Affinity DataIC50:  40nMAssay Description:Inhibition of vasopressin induced cAMP accumulation in human V2 receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135415(3-((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  40nMAssay Description:Inhibition of vasopressin induced cAMP accumulation in human V2 receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135416(Biphenyl-2-carboxylic acid {4-[2-(2-fluoro-ethyl)-...)
Affinity DataIC50:  85nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135414(Biphenyl-2-carboxylic acid {4-[2-(2-hydroxy-ethyl)...)
Affinity DataIC50:  97nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135422(Biphenyl-2-carboxylic acid {4-[2-(2,2-difluoro-eth...)
Affinity DataIC50:  100nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135414(Biphenyl-2-carboxylic acid {4-[2-(2-hydroxy-ethyl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135418(3-((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  140nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135414(Biphenyl-2-carboxylic acid {4-[2-(2-hydroxy-ethyl)...)
Affinity DataIC50:  150nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135422(Biphenyl-2-carboxylic acid {4-[2-(2,2-difluoro-eth...)
Affinity DataIC50:  160nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135416(Biphenyl-2-carboxylic acid {4-[2-(2-fluoro-ethyl)-...)
Affinity DataIC50:  180nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135415(3-((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  314nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135421(Biphenyl-2-carboxylic acid [4-(2-dimethylaminometh...)
Affinity DataIC50:  430nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135417(((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  440nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135413((5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2,3,4...)
Affinity DataIC50:  729nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135413((5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2,3,4...)
Affinity DataIC50:  740nMAssay Description:Ability to displace [3H]-arginine vasopressin in cloned human V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135420(((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  1.14E+3nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135419(2-(5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2,3...)
Affinity DataIC50:  1.15E+3nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135421(Biphenyl-2-carboxylic acid [4-(2-dimethylaminometh...)
Affinity DataIC50:  1.20E+3nMAssay Description:Ability of the compound to displace [3H]-arginine vasopressin in cloned human V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135420(((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135418(3-((S)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135417(((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}-2...)
Affinity DataIC50:  2.13E+3nMAssay Description:Inhibition of vasopressin induced calcium immobilization in human V1a receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50135415(3-((R)-5-{4-[(Biphenyl-2-carbonyl)-amino]-benzoyl}...)
Affinity DataIC50:  4.63E+3nMAssay Description:Inhibition of vasopressin induced cAMP accumulation in human V2 receptor expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed