Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50021401
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50224198((2S,3S)-N-(2-methoxy-5-(1,1,1-trifluoro-2-methylpr...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at neurokinin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50224197((2S,3S)-N-(5-tert-butyl-2-methoxybenzyl)-2-phenylp...)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at neurokinin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50160039(CHEMBL183752 | N-(4-tert-Butyl-phenyl)-4-(3-chloro...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at human TRPV1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224199(4-(3-chloropyridin-2-yl)-N-(4-(1,1,1-trifluoro-2-m...)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at human TRPV1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50191743(4-(3-chloropyridin-2-yl)-N-(4-(trifluoromethyl)phe...)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human TRPV1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed