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Found 57 Enz. Inhib. hit(s) with all data for entry = 50014774
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579971(CHEMBL5070513)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579977(CHEMBL5086139)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579976(CHEMBL5093078)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579975(CHEMBL5085591)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579984(CHEMBL5093991)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579972(CHEMBL5091214)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579981(CHEMBL5071436)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579983(CHEMBL5082525)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579979(CHEMBL5074738)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579982(CHEMBL5087403)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579980(CHEMBL5077466)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579973(CHEMBL5082704)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579978(CHEMBL5093410)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579967(CHEMBL5082990)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50541694(CHEMBL4643964)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579964(CHEMBL5077896)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579960(CHEMBL5078506)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579958(CHEMBL5070921)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579966(CHEMBL5072185)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579965(CHEMBL5078858)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579962(CHEMBL5089832)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579963(CHEMBL5078964)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579954(CHEMBL5094240)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579970(CHEMBL5077379)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579969(CHEMBL5094543)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579961(CHEMBL5078514)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579955(CHEMBL5077249)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579968(CHEMBL5072404)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579959(CHEMBL5072993)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human TNKS1 (1030 to 1317 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human TNKS1 (1030 to 1317 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579957(CHEMBL5087490)
Affinity DataIC50:  93nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50541697(CHEMBL4633637)
Affinity DataIC50:  126nMAssay Description:Inhibition of recombinant human TNKS1 (1030 to 1317 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50541697(CHEMBL4633637)
Affinity DataIC50:  127nMAssay Description:Inhibition of recombinant human TNKS1 (1030 to 1317 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579956(CHEMBL5081642)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50541697(CHEMBL4633637)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP3 (unknown origin) incubated for 4 hrs in presence of NADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP2 (unknown origin) incubated for 30 mins in presence of NADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50541697(CHEMBL4633637)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP2 (unknown origin) incubated for 30 mins in presence of NADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 30 mins in presence of NADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50541697(CHEMBL4633637)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 30 mins in presence of NADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP3 (unknown origin) incubated for 4 hrs in presence of NADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP15 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50541697(CHEMBL4633637)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP15 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50541697(CHEMBL4633637)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50541697(CHEMBL4633637)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Symeres

Curated by ChEMBL
LigandPNGBDBM50579974(CHEMBL5090849 | US20230322721, Example 154 of WO 2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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