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Found 40 Enz. Inhib. hit(s) with all data for entry = 50016935
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175561(CHEMBL198988 | N-Hydroxy-3-(4-trifluoromethyl-benz...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175531(CHEMBL199156 | N-Hydroxy-2-(4-trifluoromethyl-benz...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175544(CHEMBL198664 | N-Hydroxy-4-oxo-4-(4-trifluoromethy...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175545(CHEMBL197685 | N-Hydroxycarbamoylmethyl-4-trifluor...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175541(CHEMBL438261 | N-Hydroxycarbamoylmethyl-4-(pyridin...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175557(CHEMBL194570 | N-Hydroxy-2-[4-(pyridin-4-yloxy)-be...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175550(CHEMBL198377 | N-Hydroxy-4-oxo-4-[4-(pyridin-4-ylo...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175529(CHEMBL383560 | N-Hydroxy-3-[4-(pyridin-4-yloxy)-be...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175551(CHEMBL366010 | N-Hydroxy-4-(4-methoxy-phenyl)-4-ox...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM11328(CHEMBL83508 | Hydroxamate 9 | N-hydroxy-2-[(4-meth...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175543(CHEMBL198662 | N-Hydroxy-3-(4-methoxy-benzenesulfo...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175547(CHEMBL198048 | N-Hydroxycarbamoylmethyl-4-methoxy-...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175554(4-[4-(4-Chloro-phenoxy)-phenyl]-N-hydroxy-4-oxo-bu...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175536(3-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-N-hydroxy...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175540(4-(4-Chloro-phenoxy)-N-hydroxycarbamoylmethyl-benz...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175527(2-[4-(4-Chloro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175538(CHEMBL372377 | N-Hydroxy-4-[4-(4-imidazol-1-yl-phe...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175539(CHEMBL198393 | N-Hydroxy-3-[4-(4-imidazol-1-yl-phe...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175546(CHEMBL373285 | N-Hydroxy-2-[4-(4-imidazol-1-yl-phe...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175530(4-(4-Imidazol-1-yl-phenoxy)-piperidine-1-carboxyli...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175564(CHEMBL198634 | N-Hydroxy-2-(7-oxo-7,8-dihydro-6H-q...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175534(CHEMBL370842 | N-Hydroxy-3-(7-oxo-7,8-dihydro-6H-q...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175542(7-Oxo-7,8-dihydro-6H-quinolizine-4-carboxylic acid...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175528(CHEMBL198227 | N-Hydroxy-4-oxo-4-(7-oxo-7,8-dihydr...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175532(3-[4-(4-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175559(4-[4-(4-Fluoro-2-methyl-benzyloxy)-phenyl]-N-hydro...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175556(2-[4-(4-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175553(4-(4-Fluoro-2-methyl-benzyloxy)-N-hydroxycarbamoyl...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175558(CHEMBL198543 | N-Hydroxycarbamoylmethyl-4-phenoxy-...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175549(CHEMBL198055 | N-Hydroxy-4-oxo-4-(4-phenoxy-phenyl...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175565(CHEMBL196460 | N-Hydroxy-3-(4-phenoxy-benzenesulfo...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175548(CHEMBL198778 | N-Hydroxy-2-(4-phenoxy-benzenesulfo...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175563(CHEMBL197729 | N-Hydroxy-3-(4-prop-1-ynyloxy-benze...)
Affinity DataIC50:  121nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175552(CHEMBL194243 | N-Hydroxy-4-oxo-4-(4-prop-1-ynyloxy...)
Affinity DataIC50:  121nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175562(CHEMBL371643 | N-Hydroxycarbamoylmethyl-4-prop-1-y...)
Affinity DataIC50:  121nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175537(CHEMBL383801 | N-Hydroxy-2-(4-prop-1-ynyloxy-benze...)
Affinity DataIC50:  121nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175555(4-Butoxy-N-hydroxycarbamoylmethyl-benzamide | CHEM...)
Affinity DataIC50:  920nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175533(3-(4-Butoxy-benzenesulfonyl)-N-hydroxy-propionamid...)
Affinity DataIC50:  920nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175535(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Affinity DataIC50:  920nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
De Novo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50175560(4-(4-Butoxy-phenyl)-N-hydroxy-4-oxo-butyramide | C...)
Affinity DataIC50:  920nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed