The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
STRUCTURAL ELUCIDATION OF AIBELLIN, A NEW PEPTIDE ANTIBIOTIC WITH EFFICIENCY ENHANCING ACTIVITY ON RUMEN FERMENTATION
SHIGENORI KUMAZAWA, MINA KANDA, HIDEYUKI AOYAMA, MASAMI UTAGAWA, JUN KONDO, SEIKO SAKAMOTO, HIROYUKI OHTANI, TAKASHI MIKAWA, ISAO CHIGA, TETSUO HAYASE, TSUNEO HINO, TOSHIFUMI TAKAO, YASUTSUGU SHIMONISHI
Author information
JOURNAL FREE ACCESS

1994 Volume 47 Issue 10 Pages 1136-1144

Details
Abstract

A new peptide antibiotic, aibellin, that had the efficiency enhancing activity on rumen fermentation, was isolated from the culture broth of the fungus, Verticimonosporium ellipticum D1528, and its primary structure was elucidated from spectrometric analysis and chemical degradation. Aibellin is a 20-residue peptaibol, and it has a unique structural feature in the novel C-terminal amino alcohol. Moreover, aibellin is the first peptaibol that possesses two acidic amino acids in the C-terminal region and a Phe residue in the middle of the sequence.

Content from these authors
© Japan Antibiotics Research Association
Previous article Next article
Favorites & Alerts

Recently viewed articles
Predecessor

The Journal of Antibiotics, Series A

Share this page
feedback
 Top