AM-2604 A, A NEW ANTIVIRAL ANTIBIOTIC PRODUCED BY A STRAIN OF STREPTOMYCES

SATOSHI OMURA; HIDEKI SHIMIZU; YUZURU IWAI; KIYOIZUMI HINOTOZAWA; KAZUHIKO OTOGURO; HIROSHI HASHIMOTO; AKIRA NAKAGAWA

doi:10.7164/antibiotics.35.1632

AM-2604 A, A NEW ANTIVIRAL ANTIBIOTIC PRODUCED BY A STRAIN OF STREPTOMYCES

SATOSHI OMURA, HIDEKI SHIMIZU, YUZURU IWAI, KIYOIZUMI HINOTOZAWA, KAZUHIKO OTOGURO, HIROSHI HASHIMOTO, AKIRA NAKAGAWA

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JOURNAL FREE ACCESS

1982 Volume 35 Issue 12 Pages 1632-1637

DOI https://doi.org/10.7164/antibiotics.35.1632

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Abstract

A novel antibiotic, AM-2604 A was isolated from the fermentation broth of Streptomyces sp. AM-2604 by solvent extraction and silica gel column chromatography. The antibiotic is pale yellow needles possessing UV absorption maxima at 280 nm and 330 nm (sh). The antibiotic possesses weak activity against fungi and trichomonad and potent inhibitory activity against various RNA and DNA viruses in vitro.

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