The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
METABOLITES OF DACTYLARIA LUTEA
THE STRUCTURES OF DACTYLARIOL AND THE ANTIPROTOZOAL ANTIBIOTIC DACTYLARIN
ANNA MARIA BECKERRODNEY W. RICKARDSKARL J. SCHMALZLHo C. YICK
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1978 Volume 31 Issue 4 Pages 324-329

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Abstract

The metabolites of the predacious fungus Dactylaria lutea ROUTIEN include the anthraquinone macrosporin (2) and three hydroxylated 1, 2, 3, 4-tetrahydro derivatives of this anthraquinone, altersolanol A (5), altersolanol B (4) and dactylariol (6). The structure and relative configuration of dactylariol are established from spectroscopic studies, and its absolute configuration is proposed as 1R, 2R, 3R by virtue of its co-occurrence with alter-solanol B. Dactylarin, suggested by other authors to have the structure (1), is shown to be identical with altersolanol B (4).

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© Japan Antibiotics Research Association
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