Bacillopeptins, New Cyclic Lipopeptide Antibiotics from Bacillus subtilis FR-2

YOSHIO KAJIMURA; MASANORI SUGIYAMA; MIYUKI KANEDA

doi:10.7164/antibiotics.48.1095

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

Bacillopeptins, New Cyclic Lipopeptide Antibiotics from Bacillus subtilis FR-2

YOSHIO KAJIMURA, MASANORI SUGIYAMA, MIYUKI KANEDA

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JOURNAL FREE ACCESS

1995 Volume 48 Issue 10 Pages 1095-1103

DOI https://doi.org/10.7164/antibiotics.48.1095

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Abstract

Bacillopeptins, new iturin-group antifungal antibiotics, were isolated from the culture broth of Bacillus subtilis FR-2 obtained from the rhizosphere of garlic suffering from the basal rot caused by Fusarium oxysporum. Their structures were elucidated to be cyclic lipopeptides similar to bacillomycin L by NMR and mass spectral studies coupled with amino acid analysis. The absolute configuration of each amino acid residue was determined by chiral HPLC.

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