ANTI-MICROBIAL ACTIVITIES OF ENDURACIDIN (ENRAMYCIN) IN VITRO AND IN VIVO
1971 Volume 24 Issue 9 Pages 583-586
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1971 Volume 24 Issue 9 Pages 583-586
Enduracidin (enramycin) was found to have high order of antibacterial activity against various antibiotic-resistant strains of staphylococci, and to be free of cross-resistance with antibiotics commercially available at present. This drug was proved to be ineffective against dysentery bacillus and other gram-negative bacilli. It is believed to be an agent to which bacterial resistance hardly increases. The 50% effective dose (ED50) of enramycin in experimental Staphylococcus aureus infections in mice was proved to be 2.27 mg/kg.
