12915_2017_472_MOESM6_ESM.tif (74.48 MB)
Additional file 6: Figure S6. of A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer
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posted on 2018-01-10, 05:00 authored by Jon Peñarando, Laura López-Sánchez, Rafael Mena, Silvia Guil-Luna, Francisco Conde, Vanessa Hernández, Marta Toledano, Victoria Gudiño, Michela Raponi, Caroline Billard, Carlos Villar, César Díaz, José Gómez-Barbadillo, Juan De la Haba-Rodríguez, Kevin Myant, Enrique Aranda, Antonio Rodríguez-ArizaKaplan–Meier plots from an analysis of the correlation between eNOS (a) or iNOS (b) mRNA expression level and patient survival using the best separation. eNOS upregulation and low iNOS expression significantly decrease the 5-year survival in colorectal cancer, colon adenocarcinoma and rectum adenocarcinoma patients. Patients were divided into low or high groups based on the level of expression of the NOS isoform. Data were taken from The Human Protein Atlas database. (TIF 76270 kb)
