Title
Linking elevated HbA1c with atherogenic lipid profile among high risk cardiovascular patients at Qassim, Saudi Arabia
Authors
Rihab Akasha*, Saheem Ahmad, Rnada Abdeen, Sara Abulgasim, Heba Barnawi, Nagwan Elhussein, Rehab Hussien A, Dina Nawaf Alshammari, Nancy Elafandy & Sultan Alouffi
Affiliation
Department of Clinical Laboratory Sciences,College of Applied Medical Sciences,University of Hail, Saudi Arabia; *Corresponding author
Rihab Akasha - E - mail: ri.ali@uoh.edu.sa
Sultan Alouffi - E - mail: s.alouffi@uoh.edu.sa
Randa abdeen - E - mail: r.abdalla@uoh.edu.sa
Sara Abulgasim - Email: s.seifeldin@uoh.edu.sa
Heba Barnawi - E - mail - h.barnawi@uoh.edu.sa
Nagwan Elhussein - E - mail - n.elhussein@uoh.edu.sa
Rehab Hussien - E - mail: re.hussien@uoh.edu.sa
Dina Nawaf Alshammari - E - mail - dd.alshammari@uoh.edu.sa
Nancy Elafandy - E - mail: n.elafandy@uoh.edu.sa
Saheem Ahmad - E - mail: s.ansari@uoh.edu.sa
Article Type
Research Article
Date
Received March 1, 2024; Revised March 31, 2024; Accepted March 31, 2024, Published March 31, 2024
Abstract
The relationship between glycated hemoglobin (HbA1c) and an atherogenic lipid profile which is associated with a higher risk of cardiovascular disease is of interest. A retrospective cross-sectional study was conducted on 83 participants aged between 14 and 77 years. Their venous blood was drawn to determine the HbA1c and fasting lipid profile including total cholesterol triglycerides and high-density lipoprotein cholesterol (HDL-C) low-density lipoprotein cholesterol (LDL-C) non-HDL cholesterol and the LDL/HDL ratio were also calculated. The correlations between HbA1c levels and these lipid profile parameters were analyzed. The study showed a significant correlation between HbA1c and LDL-C non-HDL-C and the LDL/HDL ratio. Although there was no significant difference in total cholesterol levels among all groups the levels of total cholesterol and HbA1c were positively correlated. HDL-C exhibited direct correlations with HbA1c there was no correlation between HbA1c and clinical characteristics except for age. Data shows that HbA1c can be used as a predictor of dyslipidemia in diabetic patients there is a significant correlation between HbA1c and an atherogenic lipid profile which highlights the importance of glycemic control in reducing the risk of cardiovascular disease.
Keywords
HbA1c Lipid Profile Non-HDL cholesterol Atherogenic Lipoproteins LDL cholesterol
Citation
Akasha et al. Bioinformation 20(3): 212-216 (2024)
Edited by
Peter N Pushparaj
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
