2001 Volume 92 Issue 3 Pages 479-483
A 19-year-old woman with von Recklinghausen's disease was referred to our hospital because of right adrenal pheochromocytoma. The tumor was detected incidentally with the abdominal ultrasonography when she complained epigastralgia to the home doctor who treated her hypertension. Plasma and urinary catecholamines level were elevated. The tumor was removed by laparoscopy assisted adrenalectomy without pneumoperitoneum. The resected specimen was 35×60×75mm in size and weighed 70g. Pathological diagnosis was adrenomedullary pheochromocytoma. Postoperative course was uneventful. She has been well with no signs of recurrence after 7.5 years.
We reviewed 67 Japanese patients previously reported as von Recklinghausen's disease with pheochromocytoma. Of the 60 patients whose details were described, 16.7% had metastases and pathological malignacy from pheochromocytoma.