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CC BY-NC-ND 4.0 · Sleep Sci 2019; 12(03): 171-177
DOI: 10.5935/1984-0063.20190074
ORIGINAL ARTICLE

Hunger hormone and sleep responses to the built-in blue-light filter on an electronic device: a pilot study

Matthew William Driller
1   University of Waikato, Health, Sport and Human Performance - Hamilton - Waikato - New Zealand.
,
Gregory Jacobson
2   University of Waikato, Science and Engineering - Hamilton - Waikato - New Zealand.
,
Liis Uiga
1   University of Waikato, Health, Sport and Human Performance - Hamilton - Waikato - New Zealand.
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The aim of the current study was to investigate the effect of the blue-light filtering 'Night Shift' function on the Apple iPad at night and leptin production, perceived hunger levels and markers of sleep quality and quantity in healthy young adults. In a randomised, crossover design, 13 young adults (6 male/7 female) performed three experimental trials. Two of the interventions included one hour of night-time electronic device use; reading on an iPad ~30 cm from eyes, either with (iPad+NS) or without (iPad) the 'Night Shift' blue-light filtering feature turned on. The control trial involved reading a hard-copy book for one hour (CON). Leptin and perceived hunger and tiredness levels were assessed at various time points for the three experimental conditions. Objective sleep indices (actigraphy) and subjective ratings of sleep were recorded. There were no significant interactions for any of the measured variables (p > 0.05). Small to moderate effect sizes were found for perceived sleep quality, with CON (7.3 ± 1.7) having the highest value when compared to iPad+NS (6.6 ± 1.8, d = 0.29) and iPad (5.6 ± 2.3, d = 0.66). Moderate effects were associated with iPad+NS when compared to iPad (d = 0.77) and for iPad compared to CON (d = 0.90) for pre-post change in leptin concentration. Use of electronic devices at night may result in moderate suppression of leptin levels and impaired sleep quality, with negligible differences associated with whether or not the 'Night Shift' feature is turned on.

leptin - circadian rhythms - electronic device - screen time - obesity


Publication History

Received: 29 January 2019

Accepted: 27 May 2019

Article published online:
31 October 2023

© 2023. Brazilian Sleep Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • REFERENCES

  • 1 Knutson KL, Van Cauter E. Associations between sleep loss and increased risk of obesity and diabetes. Ann N Y Acad Sci. 2008; 1129(1):287-304.
  • 2 Liu Y, Croft JB, Wheaton AG, Perry GS, Chapman DP, Strine TW, et al. Association between perceived insufficient sleep, frequent mental distress, obesity and chronic diseases among US adults, 2009 behavioral risk factor surveillance system. BMC Public Health. 2013; 13(1):84.
  • 3 Hogenkamp PS, Nilsson E, Nilsson VC, Chapman CD, Vogel H, Lundberg LS, et al. Acute sleep deprivation increases portion size and affects food choice in young men. Psychoneuroendocrinology. 2013; 38(9):1668-74.
  • 4 Wells TT, Cruess DG. Effects of partial sleep deprivation on food consumption and food choice. Psychol Health. 2006; 21(1):79-86.
  • 5 Spiegel K, Tasali E, Penev P, Van Cauter E. Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med. 2004; 141(11):846-50.
  • 6 Taheri S, Lin L, Austin D, Young T, Mignot E. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004; 1(3):e62.
  • 7 van der Lely S, Frey S, Garbazza C, Wirz-Justice A, Jenni OG, Steiner R, et al. Blue blocker glasses as a countermeasure for alerting effects of evening light-emitting diode screen exposure in male teenagers. J Adolesc Health. 2015; 56(1):113-9.
  • 8 Gradisar M, Wolfson AR, Harvey AG, Hale L, Rosenberg R, Czeisler CA. The sleep and technology use of Americans: findings from the National Sleep Foundation’s 2011 Sleep in America poll. J Clin Sleep Med. 2013; 9(12):1291.
  • 9 Anderson YC, Wynter LE, Treves KF, Grant CC, Stewart JM, Cave TL, et al. Prevalence of comorbidities in obese New Zealand children and adolescents at enrolment in a community based obesity programme. J Paediatr C Health. 2016; 52(12):1099-105.
  • 10 Zeitzer JM, Dijk DJ, Kronauer RE, Brown EN, Czeisler CA. Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression. J Physiol. 2000; 526(3):695-702.
  • 11 West KE, Jablonski MR, Warfield B, Cecil KS, James M, Ayers MA, et al. Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans. J Appl Physiol. 2011; 110(3):619-26.
  • 12 Chang A-M, Aeschbach D, Duffy JF, Czeisler CA. Evening use of lightemitting eReaders negatively affects sleep, circadian timing, and nextmorning alertness. Proc Natl Acad Sci. 2015; 112(4):1232-7.
  • 13 Cheung IN, Shalman D, Malkani RG, Zee PC, Reid KJ. Evening blueenriched light exposure increases hunger and alters metabolism in normal weight adults. Sleep. 2014; 37(Supp 114).
  • 14 Ayaki M, Hattori A, Maruyama Y, Nakano M, Yoshimura M, Kitazawa M, et al. Protective effect of blue-light shield eyewear for adults against light pollution from self-luminous devices used at night. Chronobiol Int. 2016; 33(1):134-9.
  • 15 Figueiro MG, Plitnick B, Rea MS. Light modulates leptin and ghrelin in sleep-restricted adults. Int J Endocrinol; 2012.
  • 16 Szewczyk-Golec K, Wo.niak A, Reiter RJ. Inter-relationships of the chronobiotic, melatonin, with leptin and adiponectin: implications for obesity. J Pineal Res. 2015; 59(3):277-91.
  • 17 Nagare R, Plitnick B, Figueiro M. Does the iPad Night Shift mode reduce melatonin suppression? Light Res Technol. 2018; 1477153517748189.
  • 18 Casanueva FF, Dieguez C. Neuroendocrine regulation and actions of leptin. Front Endocrinol. 1999; 20(4):317-63.
  • 19 Alonso-Vale MIC, Andreotti S, Peres SB, Anhe GF, das Neves Borges- Silva C, Neto JC, et al. Melatonin enhances leptin expression by rat adipocytes in the presence of insulin. Am J Physiol Endocrinol Metabl. 2005; 288(4):E805-E12.
  • 20 Buonfiglio D, Parthimos R, Dantas R, Cerqueira Silva R, Gomes G, Andrade- Silva J, et al. Melatonin absence leads to long-Term leptin resistance and Overweight in rats. Front Endocrinol. 2018; 9:122.
  • 21 Lucas RJ, Peirson SN, Berson DM, Brown TM, Cooper HM, Czeisler CA, et al. Measuring and using light in the melanopsin age. Trends Neurosci. 2014; 37(1):1-9.
  • 22 Driller MW, O’Donnell S, Tavares F. What wrist should you wear your actigraphy device on? Analysis of dominant vs. non-dominant wrist actigraphy for measuring sleep in healthy adults. Sleep Sci; 2017.
  • 23 Russell C, Caldwell J, Arand D, Myers L, Wubbels P, Downs H. Validation of the Fatigue Science Readiband™ Actigraph and Associated Sleep/ Wake Classification Algorithms; 2011.
  • 24 Dunican IC, Murray K, Slater JA, Maddison KJ, Jones MJ, Dawson B, et al. Laboratory and home comparison of wrist-activity monitors and polysomnography in middle-aged adults. Sleep Biol Rhythms. 2018; 16(1):85-97.
  • 25 Driller M, McQuillan J, O’Donnell S. Inter-device reliability of an automatic- scoring actigraph for measuring sleep in healthy adults. Sleep Sci. 2016; 9(3):198-201.
  • 26 Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989; 28(2):193-213.
  • 27 Hopkins W, Marshall S, Batterham A, Hanin J. Progressive statistics for studies in sports medicine and exercise science Med Sci Sports Exerc. 2009; 41(1):3-12.
  • 28 Batterham A, Hopkins W. Making meaningful inferences about magnitudes. Int J Sports Physiol Perform. 2006; 1(50):50-7.
  • 29 Dallongeville J, Hecquet B, Lebel P, Edme J, Le Fur C, Fruchart J, et al. Short term response of circulating leptin to feeding and fasting in man: influence of circadian cycle. Int J Obes. 1998; 22(8):728.
  • 30 Joannic J-L, Oppert J-M, Lahlou N, Basdevant A, Auboiron S, Raison J, et al. Plasma leptin and hunger ratings in healthy humans. Appetite. 1998; 30(2):129-38.
  • 31 Kilgore W. Socio-emotional and neurocognitive effects of sleep loss. Handb Oper Fatigue. 2012; 173-85.
  • 32 Cheung IN, Zee PC, Shalman D, Malkani RG, Kang J, Reid KJ. Morning and evening blue-enriched light exposure alters metabolic function in normal weight adults. PloS One. 2016; 11(5):e0155601.
  • 33 Wood B, Rea MS, Plitnick B, Figueiro MG. Light level and duration of exposure determine the impact of self-luminous tablets on melatonin suppression. Appl Ergon. 2013; 44(2):237-40.
  • 34 Sasseville A, Paquet N, Sévigny J, Hébert M. Blue blocker glasses impede the capacity of bright light to suppress melatonin production. J Pineal Res. 2006; 41(1):73-8.
  • 35 Kus I, Sarsilmaz M, Colakoglu N, Kukner A, Ozen O, Yilmaz B, et al. Pinealectomy increases and exogenous melatonin decreases leptin production in rat anterior pituitary cells: an immunohistochemical study. Physiol Res. 2004; 53(4):403-8.
  • 36 De Almeida EA, Di Mascio P, Harumi T, Spence DW, Moscovitch A, Hardeland R, et al. Measurement of melatonin in body fluids: standards, protocols and procedures. Child Nerv Syst. 2011; 27(6):879-91.
  • 37 Voultsios A, Kennaway DJ, Dawson D. Salivary melatonin as a circadian phase marker: validation and comparison to plasma melatonin. J Biol Rhythms. 1997; 12(5):457-66.