医療薬学
Online ISSN : 1882-1499
Print ISSN : 1346-342X
ISSN-L : 1346-342X
造影剤による腎機能低下の予防を目的としたアセチルシステインゼリーの調製と評価
須田 範行新里 利香清川 真美金内 美妃菅原 満郡 修徳宮崎 勝巳
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2005 年 31 巻 5 号 p. 355-359

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Acetylcysteine is used for the prevention of radiocontrast-induced reductions in renal function. However, as an oral solution, acetylcysteine has an unpleasant taste and smell, which can cause discomfort to patients. To solve this problem, we prepared an oral jelly of acetylcysteine consisting of acetylcysteine, gelatin, flavoring agent and purified water. The unpleasant taste and smell of acetylcysteine were greatly reduced through the use of flavoring agents like apple.
We expect our acetylcysteine jelly to be a highly effective preparation for the prevention of radiocontrast-induced reductions in renal function.

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