A Case of Pyoderma Gangrenosum in the Nasal Root Associated with Ulcerative Colitis

Ryo Kanamura; Masakazu Goda; Seiichiro Kamimura; Hideyuki Nakagawa; Jiro Udaka; Koichi Tamura; Noriaki Takeda

doi:10.5631/jibirin.106.797

Original articles

A Case of Pyoderma Gangrenosum in the Nasal Root Associated with Ulcerative Colitis

Ryo Kanamura, Masakazu Goda, Seiichiro Kamimura, Hideyuki Nakagawa, Jiro Udaka, Koichi Tamura, Noriaki Takeda

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Keywords: pyoderma gangrenosum, ulcerative colitis, progressive skin necrosis, roof of nose, skin ulcer

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2013 Volume 106 Issue 9 Pages 797-802

DOI https://doi.org/10.5631/jibirin.106.797

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Abstract

We report herein on a case with pyoderma gangrenosum in the nasal root associated with ulcerative colitis. Pyoderma gangrenosum is characterized by progressive skin necrosis and is often associated with chronic bowel inflammatory diseases such as ulcerative colitis and Crohn’s disease. Although it bears a clinical resemblance to self-destructive abscesses or bacterial infection of the soft tissues, no bacteria and non-effects of antimicrobial agents were observed and the drainage of the abscess and debridement of necrotic tissue is contraindicated in patients with pyoderma gangrenosum. The treatment of the underlying disease is also effective for the treatment of pyoderma gangrenosum. In the present case, a steroid and mesalazine were effective for both the pyoderma gangrenosum and ulcerative colitis.

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