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Case Report

Primary Immune Thrombocytopenia in a Patient with Sarcoidosis

by
Marta Dąbrowska
1,*,
Rafał Krenke
1,
Marta Maskey-Warzęchowska
1,
Piotr Boguradzki
2,
Anna Waszczuk-Gajda
2,
Wiesław Wiktor Jędrzejczak
2,
Paweł Caban
3 and
Ryszarda Chazan
1
1
Department of Internal Medicine, Pneumonology and Allergy, Medical University of Warsaw, Banacha 1a St., 02-797 Warsaw, Poland
2
Department of Haematology, Oncology and Internal Medicine, Medical University of Warsaw, 02-797 Warsaw, Poland
3
Department of Thoracic Surgery, The Institute of Tuberculosis and Lung Diseases, Warsaw, Poland
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2011, 79(5), 371-376; https://doi.org/10.5603/ARM.27640
Submission received: 13 January 2011 / Revised: 22 August 2011 / Accepted: 22 August 2011 / Published: 22 August 2011

Abstract

Sarcoidosis is a disease characterised by a highly variable clinical course. While it may be accompanied by various immune disorders, it is rarely accompanied by disorders of the haematopoietic system. We report a case of sudden-onset primary immune thrombocytopenia co-existing with sarcoidosis. The prevalence of primary immune thrombocytopenia in patients with sarcoidosis is estimated at about 2% and about 1% of patients with thrombocytopenia are diagnosed with sarcoidosis. Three potential pathomechanisms leading to the development of thrombocytopenia in sarcoidosis have been described, namely: (1) the presence of antiplatelet antibodies, (2) presence of epithelioid cell granulomas in the bone marrow and (3) hypersplenism.
Keywords: sarcoidosis; primary immune thrombocytopenia; mediastinal lymph node enlargement; mediastinal lymphadenopathy sarcoidosis; primary immune thrombocytopenia; mediastinal lymph node enlargement; mediastinal lymphadenopathy

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MDPI and ACS Style

Dąbrowska, M.; Krenke, R.; Maskey-Warzęchowska, M.; Boguradzki, P.; Waszczuk-Gajda, A.; Jędrzejczak, W.W.; Caban, P.; Chazan, R. Primary Immune Thrombocytopenia in a Patient with Sarcoidosis. Adv. Respir. Med. 2011, 79, 371-376. https://doi.org/10.5603/ARM.27640

AMA Style

Dąbrowska M, Krenke R, Maskey-Warzęchowska M, Boguradzki P, Waszczuk-Gajda A, Jędrzejczak WW, Caban P, Chazan R. Primary Immune Thrombocytopenia in a Patient with Sarcoidosis. Advances in Respiratory Medicine. 2011; 79(5):371-376. https://doi.org/10.5603/ARM.27640

Chicago/Turabian Style

Dąbrowska, Marta, Rafał Krenke, Marta Maskey-Warzęchowska, Piotr Boguradzki, Anna Waszczuk-Gajda, Wiesław Wiktor Jędrzejczak, Paweł Caban, and Ryszarda Chazan. 2011. "Primary Immune Thrombocytopenia in a Patient with Sarcoidosis" Advances in Respiratory Medicine 79, no. 5: 371-376. https://doi.org/10.5603/ARM.27640

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