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Risk factors of diabetic foot of neuropathic origin in patients with type 2 diabetes
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Abstract
Introduction: Diabetic foot is a diabetes mellitus complication leading to recurrent ulcerations, risk of osteomyelitis and tissue necrosis which may finally result in amputation. Diabetic foot of neuropathic origin manifesting as autonomic and sensory motor neuropathy is the most common type of this complication. The aim of this study was to identify risk factors of diabetic foot of neuropathic origin occurrence in patients with type 2 diabetes.
Material and methods: The study included 240 patients, 74 with diabetic foot of neuropathic origin and 166 with diabetes. Cases and controls were matched in terms of age structure. Patients with peripheral arterial disease were excluded from the study. The study was conducted in the Gastroenterology and Metabolic Diseases Department, Medical University of Warsaw, Poland. We used logistic regression models, χ2, U Mann-Whitney’s and t-Student tests.
Results: Logistic regression analysis showed that diabetic foot of neuropathic origin risk factors were: male gender (OR = 6.63; 95% CI: 3.31–13.27; p = 0.00001), duration of diabetes (OR = 1.10; 95% CI: 1.06–1.14; p = 0.00001), height (OR = 1.09; 95% CI: 1.06–1.13; p = 0.00001), weight (OR = 1.04; 95% CI: 1.04–1.06; p = 0.00001) and waist circumference (OR = 1.05; 95% CI: 1.02–1.08; p = 0.001). Although there was a correlation between diabetic foot of neuropathic origin and BMI value, it had no impact on DF occurrence risk.
Conclusion: It is possible to identify patients at risk of diabetic foot development by evaluating anthropometric features. The existence of specific factors increasing the odds of diabetic foot of neuropathic origin occurring may lead to the identification of patients at risk of its development.
Abstract
Introduction: Diabetic foot is a diabetes mellitus complication leading to recurrent ulcerations, risk of osteomyelitis and tissue necrosis which may finally result in amputation. Diabetic foot of neuropathic origin manifesting as autonomic and sensory motor neuropathy is the most common type of this complication. The aim of this study was to identify risk factors of diabetic foot of neuropathic origin occurrence in patients with type 2 diabetes.
Material and methods: The study included 240 patients, 74 with diabetic foot of neuropathic origin and 166 with diabetes. Cases and controls were matched in terms of age structure. Patients with peripheral arterial disease were excluded from the study. The study was conducted in the Gastroenterology and Metabolic Diseases Department, Medical University of Warsaw, Poland. We used logistic regression models, χ2, U Mann-Whitney’s and t-Student tests.
Results: Logistic regression analysis showed that diabetic foot of neuropathic origin risk factors were: male gender (OR = 6.63; 95% CI: 3.31–13.27; p = 0.00001), duration of diabetes (OR = 1.10; 95% CI: 1.06–1.14; p = 0.00001), height (OR = 1.09; 95% CI: 1.06–1.13; p = 0.00001), weight (OR = 1.04; 95% CI: 1.04–1.06; p = 0.00001) and waist circumference (OR = 1.05; 95% CI: 1.02–1.08; p = 0.001). Although there was a correlation between diabetic foot of neuropathic origin and BMI value, it had no impact on DF occurrence risk.
Conclusion: It is possible to identify patients at risk of diabetic foot development by evaluating anthropometric features. The existence of specific factors increasing the odds of diabetic foot of neuropathic origin occurring may lead to the identification of patients at risk of its development.
Keywords
diabetic foot of neuropathic; diabetes; risk
About this articleTitle
Risk factors of diabetic foot of neuropathic origin in patients with type 2 diabetes
Journal
Issue
Article type
Original paper
Pages
10-14
Published online
2015-03-02
Page views
3099
Article views/downloads
3148
DOI
10.5603/EP.2015.0003
Pubmed
Bibliographic record
Endokrynol Pol 2015;66(1):10-14.
Keywords
diabetic foot of neuropathic
diabetes
risk
Authors
Piotr Nehring
Adam Makowski
Beata Mrozikiewicz-Rakowska
Agnieszka Sobczyk-Kopcioł
Rafał Płoski
Waldemar Karnafel
