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Tuberculosis infection in foreign-born children: a screening survey based on skin and blood testing [Short communication]

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This study, carried out in a low tuberculosis (TB) prevalence country with high immigration rates from high TB prevalence countries, deals with the interferon-gamma release assay, QuantiFERON®-TB Gold In-Tube, for the diagnosis of latent TB infection (LTBI) in foreign-born children. The results of our study highlight the potential advantages and concerns of using a blood test for diagnosing LTBI in a ‘two-step’ strategy in foreign-born children.

Keywords: active tuberculosis; foreign-born children; interferon-gamma assays; latent tuberculosis infection

Document Type: Short Communication

Affiliations: 1: Section of Respiratory Diseases, Department of Oncology, Haematology and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy 2: Department of Paediatrics, University of Modena and Reggio Emilia, Modena, Italy 3: Biostatistics Unit, Department of Oncology, Haematology and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy 4: Community Paediatrics Unit, Primary Care Trust, Local Health Service of Modena, Modena, Italy 5: Microbiology and Virology Laboratory, University-Hospital Policlinico of Modena, Modena, Italy

Publication date: 01 September 2011

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  • The International Journal of Tuberculosis and Lung Disease (IJTLD) is for clinical research and epidemiological studies on lung health, including articles on TB, TB-HIV and respiratory diseases such as COVID-19, asthma, COPD, child lung health and the hazards of tobacco and air pollution. Individuals and institutes can subscribe to the IJTLD online or in print – simply email us at [email protected] for details.

    The IJTLD is dedicated to understanding lung disease and to the dissemination of knowledge leading to better lung health. To allow us to share scientific research as rapidly as possible, the IJTLD is fast-tracking the publication of certain articles as preprints prior to their publication. Read fast-track articles.

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