BioScience Trends
Online ISSN : 1881-7823
Print ISSN : 1881-7815
ISSN-L : 1881-7815
Letter
New thoughts in exploring the pathogenesis, diagnosis, and treatment of threatened abortion
Jing Zhou, Zengshu Huang, Xinyao Pan, Wing Ting Leung, Chuyu Li, Lijia Chen, Yanzhi Zhang, Lan Wang, Yizhen Sima, Na Zhang, Xuemin Qiu, Lisha Li, Ling Wang
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Keywords: ꞵ-human chorionic gonadotropin, estrogen, threatened abortion
JOURNAL FREE ACCESS

2019 Volume 13 Issue 3 Pages 284-285

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Abstract

Threatened abortion is a common complication of pregnancy. Since the underlying mechanisms behind this condition are complicated, predicting and treating threatened abortion is a challenge for clinicians. Interestingly, a recent article in Bioscience Trends (Biosci Trends 2019; DOI: 10.5582/bst.2019.01111) revealed a higher, not lower, level of ꞵ-human chorionic gonadotropin (hCG) and estrogen during the first 6 weeks of pregnancy, suggesting a novel association between ꞵ-hCG, estrogen, and threatened abortion. Unfortunately, this study was limited by its small sample size, unconvincing trial design, and inadequate exploration of the underlying mechanisms. This low-quality evidence indicates that a higher level of ꞵ- hCG and estrogen is associated with threatened abortion. However, that work provided some new insights for further studies of threatened abortion.

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© 2019 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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