We have synthesized twelve new ionic liquids composed of an imidazolium-based cation in combination with an anion that shows antiobiotic or analgesic activity. These “BIOnic Liquids” have been tested towards their antibiotic activity in a standardized microbiological assay. A surprizingly large number of compounds shows high activity towards a set of bacteria which cannot be explained as simple cumulative effects. The general concept opens up completely new possibilities for the future development of pharmaceutically active compounds.
Graphical Abstract
BIOnic Liquids: Imidazolium-based Ionic Liquids with Antimicrobial Activity
Keywords: Ionic Liquids; Active Pharmaceutical Ingredients (API); Imidazolium Salts; Antibiotics; Antimicrobials; Analgesics
Received: 2013-6-7
Published Online: 2014-6-2
Published in Print: 2013-10-1
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