Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014, 158(1):158-160 | DOI: 10.5507/bp.2012.034

Merkel cell carcinoma. Case report

Richard Pinka, Martin Molitorb, Jiri Ehrmannc, Peter Tvrdya, Petr Michla, Jindrich Pazderaa
a Department of Oral and Maxillofacial Surgery, University Hospital Olomouc, Czech Republic
b Department of Plastic and Aesthetic Surgery, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc
c Department of Pathology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc

Background: Merkel cell carcinoma (MCC) is a rare aggressive skin tumour affecting mainly older and immuno suppressed individuals (see our review on MCC in this volume).

Aim: This is a case report describing our first experience with Merkel cell carcinoma in an elderly woman on chemo therapy for lymphoma and it covers the diagnosis, treatment and outcome.

Methods: We did a radical excision of the soft tissue in the tumor area in conjunction with total paroditectomy and resection of the body of the zygomatic bone by radical block neck dissection. The skin defect was reconstructed myocutaneous free flap by a plastic surgeon.

Results and Conclusion: At 12 months follow-up, the MCC had not recurred.

Keywords: merkel cell carcinoma, immuno supression, diagnosis, treatment

Received: November 1, 2011; Accepted: February 28, 2012; Prepublished online: June 1, 2012; Published: April 1, 2014  Show citation

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Pink, R., Molitor, M., Ehrmann, J., Tvrdy, P., Michl, P., & Pazdera, J. (2014). Merkel cell carcinoma. Case report. Biomedical papers, 158(1), 158-160. doi: 10.5507/bp.2012.034
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    References

    1. Hodgson NC. Merkel cell carcinoma: Changing Trends in the incidence. Journal of Surgical Oncology 2005;89(1):1-4. Go to original source... Go to PubMed...
    2. Goepfer H Remmier D, Silva E, Wheller B. Merkel cell carcinoma (endocrine carcinama of the skin) of the Head and Neck. Archives of otolaryngology 1984;110:707-12. Go to original source... Go to PubMed...
    3. Brenner B, Sulkes A, Rakowski E. Second neoplasmas in patiens with Merkel cell carcinoma. Cancer 2001;91:1358-62. Go to original source... Go to PubMed...
    4. Feng H, Shude M, Chang Y. Clonal integration of polyomavirus in human Merkel cell carcinoma. Science 2008;319(5866):1096-100. Go to original source... Go to PubMed...
    5. Mori Y, Hashimoto K, Tanaka K, Cui CY, Mehregan DR, Stiff MA. A study of apoptosis in Merkel cell carcinoma: an immunohistochemical, ultrastructural, DNA ladder, and TUNEL labeling study American Journal of dermathopatology 2001;23:16-23. Go to original source... Go to PubMed...
    6. Inoue T, Yoneda K, Manabi M Demitsu T. Spontaneous regression of Merkel cell carcinoma: a Comparative Study of TUNEL index and tumor-infiltrating lymphocytes Between spontaneous regression and non-regression group. Journal of Dermatological Science 2000;24:203-11. Go to original source... Go to PubMed...
    7. Cottel WI, Bailin PL, Albom MJ, Bernstein G, Braun M, Hanke CW, Sutnick TB, Swanson NA. Essentials of Mohs micrographic surgery. Journal of dermatologic surgery and oncology 1988;14:11-3. Go to original source... Go to PubMed...
    8. Brissett AE, Olsen KD, Kasperbauer JL, Lewis JE, Goellner JR, Spotts BE, Weaver AL, Strome SE. Merkel cell carcinoma of the Head and Neck: A Retrospective Case Series. Head Neck 2002;24:982-8. doi: 10.1002/hed.10153. Go to original source... Go to PubMed...
    9. Brissett AE, Olsen KD, Kasperbauer JL, Lewis JE, Goellner JR, Spotts BE, Weaver AL, Strome SE. Merkel cell carcinoma of the Head and Neck: A Retrospective Case Series. Head Neck 2002;24:982-8. doi: 10.1002/hed.10153. Go to original source... Go to PubMed...

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