Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2011, 155(2):173-180 | DOI: 10.5507/bp.2011.010

THE QUALITY OF LIFE OF PATIENTS SUFFERING FROM SCHIZOPHRENIA – A COMPARISON WITH HEALTHY CONTROLS

Monika Sidlovaa,b, Jan Praskoa, Daniela Jelenovaa, Andrea Kovacsovaa, Klara Latalovaa, Zuzana Sigmundovaa, Kristyna Vrbovaa
a Department of Psychiatry, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech Republic
b Faculty of Health Sciences, Palacky University Olomouc

Background: In the past, the first goal of schizophrenia treatment was to reduce psychotic symptoms, mainly positive symptoms. Recently, as a result of an emphasis on patient needs, the concept of quality of life (QoL) has been brought into the treatment. The goal has therefore changed from the alleviation of symptoms to improvement of the patient's satisfaction with social activities. Self-evaluations by people with schizophrenia were previously thought to lack reliability because of the presence of psychopathological symptoms and poor awareness of the disease. Recently the importance of evaluating the satisfaction of patients themselves, however, has been recognized in schizophrenia. Studies on this field showed us, that QoL data from patients with chronic mental illness were reliable and concluded that subjective QoL evaluation was applicable to such patients.

Aims: The purpose of the present study was to compare the QoL in patients suffering from schizophrenia in clinical remission with healthy controls and examine the extent of the effects of subjective cognitive functioning on QoL in these patients.

Methods: Data were obtained using the quality of life questionnaire (Quality of Life Enjoyment and Satisfaction - Q-LES-Q), and subjective questionnaire for cognitive dysfunction (Cognitive Failures Questionnaire - CFQ) for 40 schizophrenia patients in clinical remission and 40 healthy controls.

Results: Cognitive function correlates negatively with subjective QoL in patients with schizophrenia.

Keywords: Quality of life, Schizophrenia, Controls, Cognition

Received: June 20, 2010; Accepted: July 28, 2010; Published: June 1, 2011  Show citation

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Sidlova, M., Prasko, J., Jelenova, D., Kovacsova, A., Latalova, K., Sigmundova, Z., & Vrbova, K. (2011). THE QUALITY OF LIFE OF PATIENTS SUFFERING FROM SCHIZOPHRENIA – A COMPARISON WITH HEALTHY CONTROLS. Biomedical papers155(2), 173-180. doi: 10.5507/bp.2011.010
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References

  1. Revicki DA, Murray M. Assessing health-related quality of life outcomes of drug treatments for psychiatric disorders. CNS Drugs 1994;1:465476. Go to original source...
  2. Dobre D, van Jaarsveld CH, deJongste MJ, Haaijer Ruskamp FM, Ranchor AV. The effect of beta-blocker therapy on quality of life in heart failure patients: A systematic review and meta-analysis. Pharmacoepidemiol. Drug Saf 2007;16:152159. Go to original source... Go to PubMed...
  3. Browne S, Roe M, Lane A, Gervin M, Morris M, Kinsella A, Larkin C, Callaghan EO. Quality of life in schizophrenia: Relationship to sociodemographic factors, symptomatology and tardive dyskinesia. Acta Psychiatr Scand 1996;94:118124. Go to original source... Go to PubMed...
  4. Heinrichs DW, Hanlon TE, Carpenter WT Jr. The Quality of Life Scale: An instrument for rating the schizophrenic deficit syndrome. Schizophr Bull 1984;10:388398. Go to original source... Go to PubMed...
  5. Skantze K, Malm U, Dencker SJ, May PR, Corrigan P. Comparison of quality of life with standard of living in schizophrenic out-patients. Br J Psychiatry 1992;161:797801. Go to original source... Go to PubMed...
  6. Lehman AF. The effects of psychiatric symptoms on quality of life assessments among the chronic mentally ill. Eval Program Plann 1983a;6:143151. Go to original source... Go to PubMed...
  7. Lehman AF. The well-being of chronic mental patients. Arch Gen Psychiatry 1983b;40:369373. Go to original source... Go to PubMed...
  8. Awad AG, Voruganti LN, Heslegrave RJ. A conceptual model of quality of life in schizophrenia: Description and preliminary clinical validation. Qual Life Res 1997;6:2126. Go to original source... Go to PubMed...
  9. Buchanan RW, Holstein C, Breier A. The comparative efficacy and long-term effect of clozapine treatment on neuropsychological test performance. Biol Psychiatry 1994;36:717725. Go to original source... Go to PubMed...
  10. Matsui M, Sumiyoshi T, Arai H, Higuchi Y, Kurachi M. Cognitive functioning related to quality of life in schizophrenia. Prog. Neuropsychopharmacol. Biol Psychiatry 2008;32:280287. Go to original source... Go to PubMed...
  11. Meltzer HY, Thompson PA, Lee MA, Ranjan R. Neuropsychologic deficits in schizophrenia: Relation to social function and effect of antipsychotic drug treatment. Neuropsychopharmacology 1996; 14:27S33S. Go to original source... Go to PubMed...
  12. Wegener S, Redoblado-Hodge MA, Lucas S, Fitzgerald D, Harris A, Brennan J. Relative contributions of psychiatric symptoms and neuropsychological functioning to quality of life in first-episode psychosis. Aust N Z J Psychiatry 2005;39:487492. Go to original source... Go to PubMed...
  13. Tomida K, Takahashi N, Saito S, Maeno N, Iwamoto K, Yoshida K, Kimura H, Iidaka T and Ozaki N. Relationship of psychopathologi cal symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia. Psychiatry Clin Neurosci 2010;64:6269. Go to original source... Go to PubMed...
  14. Lewis R. Should cognitive deficit be a diagnostic criterion for schizophrenia? J Psychiatry Neurosci 2004;29:102113.
  15. Green MF. What are the functional consequences of neurocognitive deficits in schizophrenia? Am J Psychiatry 1996;153:321330. Go to original source...
  16. Ritsner M, Kurs R, Gibel A, Ratner Y, Endicott J. Validity of an abbreviated Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q-18) for schizophrenia, schizoaffective, and mood disorder patients. Qual Life Res 2005;14:16931703. Go to original source... Go to PubMed...
  17. Müllerova H. Mezikultúrní přenos a validace dotazníku kvality života Q-LES-Q. Psychiatrie 2001;5:8087.
  18. Larson GE, Alderton DL, Neideffer M, Underhill E. Further evidence on dimensionality and correlates of the Cognitive Failures Questionnaire. Online:.http://www.highbeam.com/ doc/1G119279197.html>.
  19. Wagle AC, Berrios GE, Ho L. The cognitive failures questionnaire in psychiatry. Compr Psychiatry 1999;40:478484. Go to original source... Go to PubMed...
  20. Broadbent DE, Cooper PF, FitzGerald P, Parkes KR. The Cognitive Failures Questionnaire (CFQ) and its correlates. Br J Clin Psychol 1982;21:116. Go to original source... Go to PubMed...
  21. Matsui M, Sumiyoshi T, Arai H, Higuchi Y, Kurachi M. Cognitive functioning related to quality of life in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2008;32:280287. Go to original source... Go to PubMed...
  22. Hofer A, Baumgartner S, Bodner T, Edlinger M, Hummer M, Kemmler G, Rettenbacher MA, Fleischhacker WW. Patient outcomes in schizophrenia II: The impact of cognition. Eur Psychiatry 2005;20:395402. Go to original source... Go to PubMed...
  23. Prouteau A, Verdoux H, Briand C, Lesage A, Lalonde P, Nicole L, Reinharz D, Stip E. Cognitive predictors of psychosocial functioning outcome in schizophrenia: A follow-up study of subjects participating in a rehabilitation program. Schizophr Res 2005;77:343353. Go to original source... Go to PubMed...
  24. Yamauchi K, Aki H, Tomotake M, Iga J, Numata S, Motoki I, Izaki Y, Tayoshi S, Kinouchi S, Sumitani S, Tayoshi S, Takikawa Y, Kaneda Y, Taniguchi T, Ishimoto Y, Ueno S, Ohmori T. Predictors of subjective and objective quality of life in outpatients with schizophrenia. Psychiatry Clin Neurosci 2008;62:404411. Go to original source... Go to PubMed...