Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2007, 151(1):113-116 | DOI: 10.5507/bp.2007.021

SPONTANEOUS SPLENIC RUPTURE IN TWO PATIENTS WITH HEMATOLOGIC MALIGNANCY

Tomas Szotkowskia, Romana Szotkowskaa, Zuzana Pikalovaa, Tomas Tichyb, Patrik Flodrb, Martin Tichyb, Dana Houserkovac, Vladimir Benysekc, Nora Zlamalovad, Vaclav Ruzickad, Karel Indraka
a Department of Hemato-oncology, Faculty of Medicine and Dentistry, Palacky University, University Hospital Olomouc, Czech Republic
b Department of Pathology, Faculty of Medicine and Dentistry, Palacky University, University Hospital Olomouc
c Department of Radiology, Faculty of Medicine and Dentistry, Palacky University, University Hospital Olomouc
d Ist Department of Surgery, Faculty of Medicine and Dentistry, Palacky University, University Hospital Olomouc

Background: Spontaneous splenic rupture (SSR) is a very rare complication described in several hundred patients, mainly as case reports. It is defined as a splenic rupture without antecedent injury. The authors of the present paper describe the only two SSR cases diagnosed at the Hemato-oncology department, coincidentally in one year. Patients: The first patient was admitted to hospital because of planned chemotherapy for relapsed hairy cell leukemia. The second was directed to the Hemato-oncology outpatient department because of anemia and painful splenomegaly diagnosed by a physician. The diagnose of hematologic malignancy (diffuse large B-cell lymphoma) was determined subsequently on the basis of histological examination of the spleen.

Conclusion: It is necessary to consider SSR not only in patients with known diagnosis of malignant disease but in the patients with negative anamnesis, too. The aim of the paper is to draw attention to the existence of this complication.

Keywords: Spontaneous splenic rupture, Hairy cell leukaemia, Diff use large B-cell lymphoma, Sudden stomach pain, Hypovolemic

Received: March 23, 2007; Accepted: May 10, 2007; Published: June 1, 2007  Show citation

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Szotkowski, T., Szotkowska, R., Pikalova, Z., Tichy, T., Flodr, P., Tichy, M., ... Indrak, K. (2007). SPONTANEOUS SPLENIC RUPTURE IN TWO PATIENTS WITH HEMATOLOGIC MALIGNANCY. Biomedical papers, 151(1), 113-116. doi: 10.5507/bp.2007.021
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