Short communication. An association between the G/A single nucleotide polymorphism within intron II of VIP gene and milk performance traits in dairy cattle

  • Marek W. Kmiec Zachodniopomorski Uniw. Technol. w Szczecinie, Wydzial Biotechnol. i Hodowli Zwierząt, Katedra Genetyki i Ogolnej Hodowli Zwierzat, Aleja Piastow 45-50, 71–033 Szczecin
  • Wioleta Grzelak Zachodniopomorski Uniw. Technol. w Szczecinie, Wydzial Biotechnol. i Hodowli Zwierząt, Katedra Genetyki i Ogolnej Hodowli Zwierzat, Aleja Piastow 45-50, 71–033 Szczecin
  • Anna M. Majewska Zachodniopomorski Uniw. Technol. w Szczecinie, Wydzial Biotechnol. i Hodowli Zwierząt, Katedra Genetyki i Ogolnej Hodowli Zwierzat, Aleja Piastow 45-50, 71–033 Szczecin
Keywords: vasoactive intestinal peptide, lactation, milk utility traits

Abstract

Single nucleotide polymorphisms (SNPs), which are present in the encoding part of the genes responsible for important breeding functions, exert an influence on the cattle’s phenotype since their function is to regulate the genes expression. In this study a G/A single nucleotide polymorphism within intron II of the vasoactive intestinal peptide (VIP) gene was detected. The study covered a herd of 185 Jersey dairy cows from the Wielkopolska Province in Poland. All possible VIP/DraI genotypes determined by using two alleles (AA, AG, GG) were examined in the herd of cows under study. The AA genotype frequency was 0.48; AG 0.22, and GG 0.30. Allele A frequency was 0.592, whereas allele G was 0.408. Analyzed VIP/DraI gene polymorphism with respect to milk utility traits showed slight statistical differences in the percentage of fat and protein content in milk of the animals with different VIP/DraI genotypes. This study could have a significant influence on dairy cattle breeding programs in the future as improvements in genetic selection methods will continue to be important in milking management.

Downloads

Download data is not yet available.

References

Chorev M, Carmel L, 2012. The function of introns. Frontiers in Genetics 3: 1-15. http://dx.doi.org/10.3389/fgene.2012.00055

Edwards AWF, 2008. G. H. Hardy (1908) and Hardy–Weinberg equilibrium. Genetics, 179: 1143-1150. http://dx.doi.org/10.1534/genetics.104.92940

El Halawani ME, Youngren OM, Pitts GR, 1997. Vasoactive intestinal peptide as the avian prolactin releasing factor. In: Perspectives in avian endocrinology (Harvey S & Etches R, eds). The Society for Endocrinology, Bristol, pp: 403-416.

Gingold H, Pilpel Y, 2011. Determinants of translation efficiency and accuracy. Mol Syst Biol 7: 481. http://dx.doi.org/10.1038/msb.2011.14

Gozes I, Avidor R, Biegon A, Baldino F Jr, 1989. Lactation elevates vasoactive intestinal peptide messenger ribonucleic acid in rat suprachiasmatic nucleus. Endocinology 124: 81-186. http://dx.doi.org/10.1210/endo-124-1-181

Hsu FR, Shia WCh, Lo WJ, Lin HCh, Chang HY, 2010. Discovering the relationship between single nucleotide polymorphisms and alternative splicing events. Proc 10th WSEAS Int Conf on Applied Informatics and Communications, and 3rd WSEAS Int Conf on Biomedical Electronics and Biomedical Informatics. Stevens Point, pp: 333-340.

Okamoto S, Okamura H, Miyake M, Takahashi Y, Takagi S, Akagi Y, Okamoto H, Ibata I, 1991. A diurnal variation of VIP mRNA under a daily light-dark cycle in the rat suprachiasmatic nucleus. Histochem 95: 525-528. http://dx.doi.org/10.1007/BF00315750

Parmley JL, Hurst LD, 2007. How do synonymous mutations affect fitness? Bioessays 29: 515-519. http://dx.doi.org/10.1002/bies.20592

Said SI, Filippatos GS, Gangopadhyay N, Lalude O, Parameswaran N, Spielman W, Uhal BD, 2001. Regulation of apoptosis by vasoactive peptides. Am J Physiol Lung Cell Mol Physiol 281(4): 749-761.

Shabalina SA, Ogurtsov AY, Spiridonov NA, 2006. A periodic pattern of mRNA secondary structure created by the genetic code. Nucl Acids Res 34: 2428-2437. http://dx.doi.org/10.1093/nar/gkl287

Sherwood NM, Kruecki SL, McRory JE, 2000. The origin and function of the pituitary adenylate–cyclase activating polypeptide glucagon superfamily. Endocr Rev 21: 619-670.

The Bovine Map Consortium, 2009. Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science 324: 528-532. http://dx.doi.org/10.1126/science.1167936

Youngren OM, Pitts GR, Phillips RE, El Halawani ME, 1996. Dopaminergic control of prolactin in the turkey. Neuroendocrinology 104: 225-230.

Published
2014-07-07
How to Cite
Kmiec, M. W., Grzelak, W., & Majewska, A. M. (2014). Short communication. An association between the G/A single nucleotide polymorphism within intron II of VIP gene and milk performance traits in dairy cattle. Spanish Journal of Agricultural Research, 12(3), 672-675. https://doi.org/10.5424/sjar/2014123-5283
Section
Animal breeding, genetics and reproduction