Human Bioresources Papers
The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis
Authors:
- Eliana M LacerdaEmail Eliana M Lacerda
- Erinna W Bowman
- Jacqueline M Cliff
- Caroline C Kingdon
- Elizabeth C King
- Ji-Sook Lee
- Taane G Clark
- Hazel M Dockrell
- Eleanor M Riley
- Hayley Curran
- Luis Nacul
Abstract
The UK ME/CFS Biobank was launched in August 2011 following extensive consultation with professionals and patient representatives. The bioresource aims to enhance research on myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), related to pathophysiology, biomarkers and therapeutic approaches. The cohort includes 18–60 year olds, encompassing 284 clinically-confirmed ME/CFS cases, 60 neurologist-diagnosed multiple sclerosis (MS) cases, and 135 healthy individuals. The Biobank contains blood samples, aliquoted into serum, plasma, peripheral blood mononuclear cells (PBMC), red blood cells/granulocyte pellet, whole blood, and RNA (totalling 29,863 aliquots). Extensive dataset (700 clinical and socio-demographic variables/participant) enables comprehensive phenotyping. Potential reuse is conditional to ethical approval.
- Year: 2017
- Volume: 4
- Page/Article: 4
- DOI: 10.5334/ojb.28
- Published on 20 Feb 2017
- Peer Reviewed