Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations

Przemysław Zakowicz; Paweł Wójciak; Sebastian Dziuda; Filip Rybakowski

doi:10.5114/ppn.2019.84356

eISSN: 2720-5371
ISSN: 1230-2813

Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii

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abstract:

Case report

Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations

Przemysław Zakowicz

¹

,

Paweł Wójciak

¹

,

Sebastian Dziuda

¹

,

Filip Rybakowski

¹

Department of Adult Psychiatry, Poznań University of Medical Sciences, Poznań, Poland

Adv Psychiatry Neurol 2019; 28 (1): 70-77

DOI: https://doi.org/10.5114/ppn.2019.84356

Online publish date: 2019/03/30

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AMA

Zakowicz P, Wójciak P, Dziuda S, Rybakowski F. Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations. Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii. 2019;28(1):70-77. doi:10.5114/ppn.2019.84356.

APA

Zakowicz, P., Wójciak, P., Dziuda, S.,  & Rybakowski, F. (2019). Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations. Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii, 28(1), 70-77. https://doi.org/10.5114/ppn.2019.84356

Chicago

Zakowicz, Przemysław, Paweł Wójciak, Sebastian Dziuda,  and Filip Rybakowski. 2019. "Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations". Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii 28 (1): 70-77. doi:10.5114/ppn.2019.84356.

Harvard

Zakowicz, P., Wójciak, P., Dziuda, S.,  and Rybakowski, F. (2019). Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations. Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii, 28(1), pp.70-77. https://doi.org/10.5114/ppn.2019.84356

MLA

Zakowicz, Przemysław et al. "Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations." Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii, vol. 28, no. 1, 2019, pp. 70-77. doi:10.5114/ppn.2019.84356.

Vancouver

Zakowicz P, Wójciak P, Dziuda S, Rybakowski F. Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations. Advances in Psychiatry and Neurology/Postępy Psychiatrii i Neurologii. 2019;28(1):70-77. doi:10.5114/ppn.2019.84356.

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Purpose
Despite progress in the treatment of schizophrenia, treatment resistance is reported in about 30% of patients. Various forms of treatment augmentation are used, but clozapine is generally considered to be the gold standard of care. In the management of patients with clozapine resistance adjunctive electroconvulsive therapy (ECT) courses have been proposed. In recent years particular attention has been paid to augmentation of clozapine with the maintenance electroconvulsive therapy (M-ECT).

Case description
The paper presents a patient with treatment-resistant schizophrenia and chronic psychotic symptoms leading to self-destructive and suicidal behaviors. After concurrent treatment with clozapine and M-ECT her clinical status and functioning have improved.

Comment
Maintenance-ECT used to augment clozapine in drug-resistant schizophrenia seems to be a safe and promising mana¬gement option.

keywords:

Clozapine and maintenance electroconvulsive therapy in a 35-year-old patient with treatment-resistant schizophrenia and chronic imperative auditory hallucinations

Przemysław Zakowicz 1 , Paweł Wójciak 1 , Sebastian Dziuda 1 , Filip Rybakowski 1

schizophrenia, drug resistance, clozapine, maintenance electroconvulsive therapy

Przemysław Zakowicz

¹

,

Paweł Wójciak

¹

,

Sebastian Dziuda

¹

,

Filip Rybakowski

¹