V2O5/SiO2 as an efficient catalyst in the synthesis of 5-amino- pyrazole derivatives under solvent free condition

Abstract

An efficient and facile approach for the synthesis of 5-aminopyrazoles from ketene S,N-acetal and hydrazine hydrate via catalytic reaction under solvent free condition has been described. V₂O₅/SiO₂ as a heterogeneous catalyst was prepared and characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and scanning electron microscope (SEM).

KEY WORDS: One-pot synthesis, 5-Amino-1H-pyrazole, Hydrazine hydrate, Vanadium oxide, Silica

Bull. Chem. Soc. Ethiop. 2019, 33(1), 135-142

DOI: https://dx.doi.org/10.4314/bcse.v33i1.13