Pure Red Cell Aplasia and Associated Thymoma
by
Cristian Rosu
1, 
Sandra Cohen
2,
Caroline Meunier
3,
Denise Ouellette
1,
Gilles Beauchamp
1 and
George Rakovich
1,* 1
Division of Thoracic Surgery, Canada
2
Division of Hematology, Canada
3
Department of Pathology, Hôpital Maisonneuve-Rosemont, University of Montreal, Montreal, Canada
*
Author to whom correspondence should be addressed.
Clin. Pract. 2011, 1(1), e1; https://doi.org/10.4081/cp.2011.e1
Submission received: 10 March 2011
/
Revised: 10 March 2011
/
Accepted: 21 March 2011
/
Published: 1 April 2011
Abstract
Pure red cell aplasia is a rare cause of anemia, caused by an absence of red blood cell precursors in the bone marrow. It is usually a paraneoplastic syndrome, associated most commonly with large-cell granular lymphocyte leukemia but also thymoma. For patients who present both pure red cell aplasia and thymoma, thymectomy leads to an initial remission of the aplasia in 30% of cases. However, sustained remission may require the addition of medications such as corticosteroids, cyclosporine, or cyclophosphamide. We present a case of pure red cell aplasia associated with a thymoma in an otherwise healthy 80 year-old woman.
Keywords:
anemia; pure red cell aplasia; thymoma; paraneoplastic syndrome
Share and Cite
MDPI and ACS Style
Rosu, C.; Cohen, S.; Meunier, C.; Ouellette, D.; Beauchamp, G.; Rakovich, G. Pure Red Cell Aplasia and Associated Thymoma. Clin. Pract. 2011, 1, e1. https://doi.org/10.4081/cp.2011.e1
AMA Style
Rosu C, Cohen S, Meunier C, Ouellette D, Beauchamp G, Rakovich G. Pure Red Cell Aplasia and Associated Thymoma. Clinics and Practice. 2011; 1(1):e1. https://doi.org/10.4081/cp.2011.e1
Chicago/Turabian StyleRosu, Cristian, Sandra Cohen, Caroline Meunier, Denise Ouellette, Gilles Beauchamp, and George Rakovich. 2011. "Pure Red Cell Aplasia and Associated Thymoma" Clinics and Practice 1, no. 1: e1. https://doi.org/10.4081/cp.2011.e1
