Experimental Bio-ESPI for Validation of Magnetic Induced Deformation on HeLa Cells

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Abstract:

The determination of mechanical properties can provide insight into complex biochemical processes such as the cell cycle and even the progression of diseases. However, this field of biomechanical research strongly depends on a high-resolution measurement technology and a gentle stimulation method in order to examine these mostly biological samples in their original condition. In terms of this work, a different approach utilizing a modified ESPI setup and two types of ferro-fluids is presented. By exposing the prepared specimen to an electro-magnetic field it has been possible to induce a local displacement and to monitor the deformation with the adapted ESPI setup.

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1141-1146

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November 2016

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