New Injectable Bone Substitute Using Reversible Thermosensitive Hydrogel and BCP Granules: In Vivo Rabbit Experiments

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Abstract:

We have developed a new injectable bone substitute combining specific granules of BCP with or without radiopaque elements with a reversible thermo sensitive resorbable carrier such as Pluronic F-127. The composite is liquid at ambient temperature and set as hydrogel at 37°C. Rabbit experiment demonstrates high biocompatibility and bone ingrowth at the expense of the injectable bioceramic composite.

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Info:

Periodical:

Key Engineering Materials (Volumes 396-398)

Pages:

457-460

Citation:

Online since:

October 2008

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