pISSN 2093-2340   eISSN 2092-6448
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    Infect Chemother. 2011 Feb;43(1):68-71. Korean.
    Published online Feb 28, 2011.
    https://doi.org/10.3947/ic.2011.43.1.68
    Copyright © 2011 by The Korean Society of Infectious Diseases and Korean Society for Chemotherapy
    Case Report

    Testicular Tuberculosis That Mimicked Testicular Cancer

    Won Jin Kim, Kyung Hwa Shin, Mi Hyun Kim, Woo Hyun Cho, Kwangha Lee, Ki Uk Kim, Doo Soo Jeon, Hye-Kyung Park, Yun Seong Kim, Min Ki Lee and Soon Kew Park
      • Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
    • Correspondence to Ki Uk Kim, M.D. Department of Internal Medicine, Pusan National University Hospital, 1-10 Ami-dong, Seo-gu, Busan 602-739, Korea. Tel: +82.51-240-7804, Fax: +82.51-254-3127, Email: uk303@hanmail.net
    Received July 07, 2010; Revised July 22, 2010; Accepted September 20, 2010.

    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Abstract

    Next to lymphatic involvement, genitourinary tuberculosis is considered the second most common manifestation of extrapulmonary tuberculosis worldwide. However, testicular and spermatic cord involvement is uncommon. We report here on a case of testicular and spermatic cord tuberculosis that masqueraded as testicular cancer. A 25-year-old man was admitted to our hospital with painless right scrotal swelling for past 2 months. The abdominal CT scan showed a heterogenous testicular mass that was suspicious for being malignancy. He underwent right radical orchiectomy; testicular and spermatic cord tuberculosis was revealed on histopathological examination. This case highlights the importance of taking a thoughtful diagnostic approach for testicular and spermatic cord tuberculosis, including fine needle aspiration before performing surgical exploration.

    Keywords
    Urogenital tuberculosis; Urogenital cancer; Testicular cancer

    Figures

    Figure 1
    On the ultrasonographic images, the right testis shows enlargement and inhomogeneous echogenecity. On the color Doppler images, the right testis shows increased vascularity (A). The enhanced CT scan reveals an enlarged right testis, which demonstrated inhomogenous density and necrotic foci (B).

    Figure 2
    The chest radiograph shows fibrocalcified nodules in both upper lobes (A). The chest CT reveals centrilobular nodules and a tree-in bud pattern in both upper lobes (B).

    Figure 3
    Pathologic examination demonstrats normal testicular tissue on the left lower corner, while with necrotizing granulomas and Langerhans cells (arrows) on the center (H&E stain, ×100).

    References

      1. Jacob JT, Nguyen TM, Ray SM. Male genital tuberculosis. Lancet Infect Dis 2008;8:335–342.
      1. Biswas M, Rahi R, Tiwary SK, Khanna R, Khanna AK. Isolated tuberculosis of testis. Kathmandu Univ Med J (KUMJ) 2006;4:98–99.
      1. Korea Center for Disease Control and Prevention, Korean Institute of Tuberculosis. Annual report on the notified tuberculosis patients in Korea. Seoul: Korea Center for Disease Control and Prevention, Korean Institute of Tuberculosis; 2008.
      1. Kulchavenya E, Khomyakov V. Male genital tuberculosis in Siberians. World J Urol 2006;24:74–78.
      1. Gokce G, Kilicarslan H, Ayan S, Tas F, Akar R, Kaya K, Gultekin EY. Genitourinary tuberculosis: a review of 174 cases. Scand J Infect Dis 2002;34:338–340.
      1. Lee Y, Huang W, Huang J, Wang J, Yu C, Jiaan B, Huang J. Efficacy of chemotherapy for prostatic tuberculosis-a clinical and histologic follow-up study. Urology 2001;57:872–877.
      1. Moussa OM, Eraky I, El-Far MA, Osman HG, Ghoneim MA. Rapid diagnosis of genitourinary tuberculosis by polymerase chain reaction and non-radioactive DNA hybridization. J Urol 2000;164:584–588.
      1. Hemal AK, Gupta NP, Rajeev TP, Kumar R, Dar L, Seth P. Polymerase chain reaction in clinically suspected genitourinary tuberculosis: comparison with intravenous urography, bladder biopsy, and urine acid fast bacilli culture. Urology 2000;56:570–574.
      1. Torrea G, Van de Perre P, Ouedraogo M, Zougba A, Sawadogo A, Dingtoumda B, Diallo B, Defer MC, Sombié I, Zanetti S, Sechi LA. PCR-based detection of the Mycobacterium tuberculosis complex in urine of HIV-infected and uninfected pulmonary and extrapulmonary tuberculosis patients in Burkina Faso. J Med Microbiol 2005;54:39–44.
      1. Wang LJ, Wong YC, Chen CJ, Lim KE. CT features of genitourinary tuberculosis. J Comput Assist Tomogr 1997;21:254–258.
      1. Doherty FJ. Ultrasound of the nonacute scrotum. Semin Ultrasound CT MR 1991;12:131–156.
      1. Cassidy FH, Ishioka KM, McMahon CJ, Chu P, Sakamoto K, Lee KS, Aganovic L. MR imaging of scrotal tumors and pseudotumors. Radiographics 2010;30:665–683.
    MeSH Terms
    Adult
    Biopsy, Fine-Needle
    Humans
    Spermatic Cord
    Testicular Neoplasms
    Tuberculosis
    Tuberculosis, Urogenital
    Urogenital Neoplasms
    Metrics
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