Download PDF
J Am Acad Audiol 2019; 30(10): 896-903
DOI: 10.3766/jaaa.18038
Articles
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Toward An Exploration of Habituating to Tinnitus: Perspectives on Sensory Gating

Mehrnaz Mohebbi
*   ENT and Head & Neck Research Center and Department, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
,
Mohammad Farhadi
*   ENT and Head & Neck Research Center and Department, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
,
Ahmad Daneshi
*   ENT and Head & Neck Research Center and Department, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
,
Saeid Mahmoudian
*   ENT and Head & Neck Research Center and Department, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
†   Department of Otorhinolaryngology, Hannover Medical University (MHH), Hannover, Germany
› Author Affiliations
Further Information

Publication History

12 August 2018

Publication Date:
25 May 2020 (online)

   Permissions and Reprints

Abstract

Background:

Some tinnitus participants habituate to their tinnitus, but some others do not and complain of its annoyance so much. It has been suggested that tinnitus is a habituation deficit. Habituation and the ability to ignore a sensory input depend on the normal function of filtering mechanism of sensory gating.

Purpose:

The purpose of this study was to compare behavioral aspects of sensory gating in normal and tinnitus participants to search for the reason why some tinnitus participants habituate to their tinnitus but some others do not.

Research Design:

This investigation was an observational case–control study.

Study Sample:

There were 60 tinnitus participants who were categorized into two tinnitus groups (30 compensated tinnitus participants and 30 decompensated tinnitus participants) based on the complaint of tinnitus annoyance, visual analog scale (VAS) for tinnitus loudness, annoyance, and awareness, scores on Tinnitus Questionnaire (TQ), and Tinnitus Handicap Inventory (THI). Also, there were 30 normal hearing participants without tinnitus as the normal control group.

Data Collection and Analysis:

Sensory Gating Inventory (SGI), TQ, THI, and VAS was obtained from all participants. THI, TQ, VAS, and SGI total scores and their factors were compared among the groups. Correlations between SGI scores with THI, TQ, and VAS score were calculated.

Results:

The results showed that SGI total score and the scores of its four factors were significantly higher in decompensated tinnitus participants compared with compensated tinnitus participants and normal controls. Also, there was a positive correlation between SGI perceptual modulation factor and TQ emotional distress factor and with the VAS for loudness in decompensated tinnitus group.

Conclusions:

These results suggested that tinnitus associated with behavioral aspects of sensory gating and decompensated tinnitus may be a result of deficient sensory gating.

Key Words

habituation - questionnaire - sensory gating - tinnitus

This work was funded by the Iran Ministry of Health (MoH), Ph.D. students’ research program award, no. 271/7.11.2016, as a part of Ph.D. thesis.


 

  • REFERENCES

  • Adler LE, Olincy A, Waldo M, Harris JG, Griffith J, Stevens K, Flach K, Nagamoto H, Bickford P, Leonard S, Freedman R. 1998; Schizophrenia, sensory gating, and nicotinic receptors. Schizophr Bull 24 (02) 189-202
    CrossrefPubMedGoogle Scholar
  • Andersson G. 2002; Psychological aspects of tinnitus and the application of cognitive–behavioral therapy. Clin Psychol Rev 22 (07) 977-990
    CrossrefPubMedGoogle Scholar
  • Attias J, Bresloff I, Furman V, Urbach D. 1995; Auditory event related potentials in simulated tinnitus. J Basic Clin Physiol Pharmacol 6 (02) 173-184
    PubMedGoogle Scholar
  • Baguley DM. 2003; Hyperacusis. J R Soc Med 96 (12) 582-585
    CrossrefPubMedGoogle Scholar
  • Biederman J. 2005; Attention-deficit/hyperactivity disorder: a selective overview. Biol Psychiatry 57 (11) 1215-1220
    CrossrefPubMedGoogle Scholar
  • Braff DL, Geyer MA. 1990; Sensorimotor gating and schizophrenia. Human and animal model studies. Arch Gen Psychiatr 47 (02) 181-188
    CrossrefPubMedGoogle Scholar
  • Carlsson SG, Erlandsson SI. 1991; Habituation and tinnitus: an experimental study. J Psychosom Res 35 4–5 509-514
    CrossrefPubMedGoogle Scholar
  • Cromwell HC, Mears RP, Wan L, Boutros NN. 2008; Sensory gating: a translational effort from basic to clinical science. Clin EEG Neurosci 39 (02) 69-72
    CrossrefPubMedGoogle Scholar
  • Cuny C, Norena A, El Massioui F, Chéry-Croze S. 2004; Reduced attention shift in response to auditory changes in subjects with tinnitus. Audiol and Neurotol 9 (05) 294-302
    Google Scholar
  • De Ridder D, Elgoyhen AB, Romo R, Langguth B. 2011; Phantom percepts: tinnitus and pain as persisting aversive memory networks. Proc Natl Acad Sci 108 (20) 8075-8080
    CrossrefPubMedGoogle Scholar
  • De Ridder D, Fransen H, Francois O, Sunaert S, Kovacs S, Van De Heyning P. 2006; Amygdalohippocampal involvement in tinnitus and auditory memory. Acta Otolaryngol Suppl 126 (556) 50-53
    CrossrefPubMedGoogle Scholar
  • Dornhoffer J, Danner C, Mennemeier M, Blake D, Garcia-Rill E. 2006; Arousal and attention deficits in patients with tinnitus. Int Tinnitus J 12 (01) 9-16
    PubMedGoogle Scholar
  • El-Kaim A, Aramaki M, Ystad S, Kronland-Martinet R, Cermolacce M, Naudin J, Vion-Dury J, Micoulaud-Franchi J-A. 2015; On the correlation between perceptual inundation caused by realistic immersive environmental auditory scenes and the sensory gating inventory in schizophrenia. Eur Psychiatry J Assoc Eur Psychiatrists 30 (05) 606-614
    Google Scholar
  • Hallam RS, Jakes SC, Hinchcliffe R. 1988; Cognitive variables in tinnitus annoyance. Br J Clin Psychol 27 (03) 213-222
    CrossrefPubMedGoogle Scholar
  • Hetrick WP, Erickson MA, Smith DA. 2012; Phenomenological dimensions of sensory gating. Schizophr Bull 38 (01) 178-191
    CrossrefPubMedGoogle Scholar
  • Hwang JH, Chou PH, Wu CW, Chen JH, Liu TC. 2009; Brain activation in patients with idiopathic hyperacusis. Am J Otolaryngol 30 (06) 432-434
    CrossrefPubMedGoogle Scholar
  • Jacobson GP, McCaslin DL. 2003; A reexamination of the long latency N1 response in patients with tinnitus. J Am Acad Audiol 14 (07) 393-400
    Article in Thieme ConnectPubMedGoogle Scholar
  • Jastreboff PJ, Azell JWP. 1993; A neurophysiological approach to tinnitus: clinical implications. Br J Audiol 27 (01) 7-17
    CrossrefPubMedGoogle Scholar
  • Joos K, Gilles A, Van de Heyning P, De Ridder D, Vanneste S. 2014; From sensation to percept: the neural signature of auditory event-related potentials. Neurosci Biobehav Rev 42: 148-156
    CrossrefPubMedGoogle Scholar
  • Kaltenbach JA. 2006; The dorsal cochlear nucleus as a participant in the auditory, attentional and emotional components of tinnitus. Hear Res 216–217: 224-234
    PubMedGoogle Scholar
  • Khalfa S, Dubal S, Veuillet E, Perez-Diaz F, Jouvent R, Collet L. 2002; Psychometric normalization of a hyperacusis questionnaire. ORL J Otorhinolaryngol Relat Spec 64 (06) 436-442
    CrossrefPubMedGoogle Scholar
  • Kisley MA, Noecker TL, Guinther PM. 2004; Comparison of sensory gating to mismatch negativity and self-reported perceptual phenomena in healthy adults. Psychophysiology 41 (04) 604-612
    CrossrefPubMedGoogle Scholar
  • Knipper M, Van Dijk P, Nunes I, Rüttiger L, Zimmermann U. 2013; Advances in the neurobiology of hearing disorders: recent developments regarding the basis of tinnitus and hyperacusis. Prog Neurobiol 111: 17-33
    CrossrefPubMedGoogle Scholar
  • Konadath S, Manjula P. 2016; Auditory brainstem response and late latency response in individuals with tinnitus having normal hearing. Intract Rare Dis Res 5 (04) 262-268
    Google Scholar
  • Leaver AM, Renier L, Chevillet MA, Morgan S, Kim HJ, Rauschecker JP. 2011; Dysregulation of limbic and auditory networks in tinnitus. Neuron 69 (01) 33-43
    CrossrefPubMedGoogle Scholar
  • Lijffijt M, Lane SD, Meier SL, Boutros NN, Burroughs S, Steinberg JL, Gerard Moeller F, Swann AC. 2009; P50, N100, and P200 sensory gating: relationships with behavioral inhibition, attention, and working memory. Psychophysiology 46 (05) 1059-1068
    CrossrefPubMedGoogle Scholar
  • Lim JJBH, Lu PKS, Koh DSQ, Eng SP. 2010; Impact of tinnitus as measured by the Tinnitus Handicap inventory among tinnitus sufferers in Singapore. Singapore Med J 51 (07) 551-557
    PubMedGoogle Scholar
  • Low YF, Trenado C, Delb W, Corona-Strauss FI, Strauss DJ. 2007; The role of attention in the tinnitus decompensation: reinforcement of a large-scale neural decompensation measure. Conf Proc IEEE Eng Med Biol Soc 2007: 2485-2488
    PubMedGoogle Scholar
  • Mahmoudian S, Farhadi M, Najafi-Koopaie M, Darestani-Farahani E, Mohebbi M, Dengler R, Esser KH, Sadjedi H, Salamat B, Danesh AA, Lenarz T. 2013; Central auditory processing during chronic tinnitus as indexed by topographical maps of the mismatch negativity obtained with the multi-feature paradigm. Brain Res 1527: 161-173
    CrossrefPubMedGoogle Scholar
  • McGhie A, Chapman J. 1961; Disorders of attention and perception in early schizophrenia. Br J Med Psychol 34 (02) 103-116
    CrossrefPubMedGoogle Scholar
  • Meric C, Gartner M, Collet L, Chéry-Croze S. 1998; Psychopathological profile of tinnitus sufferers: evidence concerning the relationship between tinnitus features and impact on life. Audiol Neuro Otol 3 (04) 240-252
    CrossrefPubMedGoogle Scholar
  • Micoulaud-Franchi JA, Vion-Dury J. 2013; What is sensory inundation in schizophrenia?. Clin Neurophysiol 124 (03) 628-629
    CrossrefPubMedGoogle Scholar
  • Micoulaud-Franchi J-A, Hetrick WP, Aramaki M, Bolbecker A, Boyer L, Ystad S, Kronland-Martinet R, Richieri R, Faget C, Faugere M, El-Kaim A, Cermolacce M, Lancon C, Vion-Dury J. 2014; Do schizophrenia patients with low P50-suppression report more perceptual anomalies with the sensory gating inventory?. Schizophr Res 157 1–3 157-162
    CrossrefPubMedGoogle Scholar
  • Micoulaud-Franchi JA, Lopez R, Cermolacce M, Vaillant F, Péri P, Boyer L, Richieri R, Bioulac S, Sagaspe P, Philip P, Vion-Dury J, Vion-Dury J. 2016; Sensory gating capacity and attentional function in adults with ADHD: a preliminary neurophysiological and neuropsychological study. J Atten Disord 1087054716629716
    Google Scholar
  • Møler AR. 1999 , September Pathophysiology of severe tinnitus and chronic pain. In: Sixth International Tinnitus Seminar (p. 26)
    PubMedGoogle Scholar
  • Møller AR. 2003; Pathophysiology of tinnitus. Otolaryngol Clin North Am 36 (02) 249-266
    CrossrefPubMedGoogle Scholar
  • Oldfield RC. 1971; The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9 (01) 97-113
    CrossrefPubMedGoogle Scholar
  • Pienkowski M, Tyler RS, Roncancio ER, Jun HJ, Brozoski T, Dauman N, Martin N. 2014; A review of hyperacusis and future directions: part II. Measurement, mechanisms, and treatment. Am J Audiol 23 (04) 420-436
    CrossrefPubMedGoogle Scholar
  • Rauschecker JP, Leaver AM, Mühlau M. 2010; Tuning out the noise: limbic-auditory interactions in tinnitus. Neuron 66 (06) 819-826
    CrossrefPubMedGoogle Scholar
  • Rauschecker JP, May ES, Maudoux A, Ploner M. 2015; Frontostriatal gating of tinnitus and chronic pain. Trends Cogn Sci 19 (10) 567-578
    CrossrefPubMedGoogle Scholar
  • Sable JJ, Kyle MR, Knopf KL, Schully LT, Brooks MM, Parry KH, Diamond RE, Flink LA, Stowe R, Suna E, Thompson IA. 2012; The Sensory Gating Inventory as a potential diagnostic tool for attention-deficit hyperactivity disorder. Atten Defic Hyperact Disord 4 (03) 141-144
    CrossrefPubMedGoogle Scholar
  • Stobik C, Weber RK, Münte TF, Walter M, Frommer J. 2005; Evidence of psychosomatic influences in compensated and decompensated tinnitus. Int J Audiol 44 (06) 370-378
    CrossrefPubMedGoogle Scholar
  • Strauss DJ, Delb W, D’Amelio R, Low YF, Falkai P. 2008; Objective quantification of the tinnitus decompensation by synchronization measures of auditory evoked single sweeps. Trans Neural Syst Rehabil Eng 16 (01) 74-81
    Google Scholar
  • Sutherland Owens AN, Miguel EC, Swerdlow NR. 2011; Sensory gating scales and premonitory urges in Tourette syndrome. Sci World J 11: 736-741
    CrossrefPubMedGoogle Scholar
  • Tyler RS, Conrad-Armes D. 1983; The determination of tinnitus loudness considering the effects of recruitment. J Speech Lang Hear Res 26 (01) 59-72
    CrossrefPubMedGoogle Scholar
  • Tyler RS, Erlandsson S. 2003; Management of the tinnitus patient. Textbook of Audiological Medicine, 571-578
    Google Scholar
  • Tyler RS, Pienkowski M, Roncancio ER, Jun HJ, Brozoski T, Dauman N, Andersson G, Keiner AJ, Cacace AT, Martin N, Moore BC, Martin N. 2014; A review of hyperacusis and future directions: part I. Definitions and manifestations. Am J Audiol 23 (04) 402-419
    CrossrefPubMedGoogle Scholar
  • Vendrig AA. 2000; The Minnesota Multiphasic Personality Inventory and chronic pain: a conceptual analysis of a long-standing but complicated relationship. Clin Psychol Rev 20: 533-559
    CrossrefPubMedGoogle Scholar
  • Walpurger V, Hebing-Lennartz G, Denecke H, Pietrowsky R. 2003; Habituation deficit in auditory event-related potentials in tinnitus complainers. Hear Res 181 1–2 57-64
    CrossrefPubMedGoogle Scholar
  • Weisz N, Voss S, Berg P, Elbert T. 2004; Abnormal auditory mismatch response in tinnitus sufferers with high-frequency hearing loss is associated with subjective distress level. BMC Neuroci 5 (01) 8
    Google Scholar
  • Yochman A, Ornoy A, Parush S. 2006; Co-occurrence of developmental delays among preschool children with attention-deficit–hyperactivity disorder. Dev Med Child Neurol 48 (06) 483
    CrossrefPubMedGoogle Scholar
  • Zeng FG. 2013; An active loudness model suggesting tinnitus as increased central noise and hyperacusis as increased nonlinear gain. Hear Res 295: 172-179
    CrossrefPubMedGoogle Scholar