Direct Conjugation of Resveratrol on Hydrophilic Gold Nanoparticles: Structural and Cytotoxic Studies for Biomedical Applications
Abstract
:1. Introduction
2. Experimental Part
2.1. Materials and Methods
2.2. Synthesis and Purification of AuNPs
2.3. AuNPs@RSV Preparations and Characterizations
2.4. Cell Lines and In Vitro Assays
2.4.1. Cell Culture and Stimulation
2.4.2. Western Blot Assay
2.4.3. Propidium Iodide (PI) Assay
2.4.4. Statistical Analysis.
3. Results and Discussion
3.1. Synthesis and Characterizations of AuNPs and AuNPs@RSV
3.2. Structural Characterizations of AuNPs and AuNPs@RSV
3.2.1. SR-XPS Characterization
3.2.2. FT-IR Characterization
3.2.3. NEXAFS Characterization
3.3. AuNPs and AuNPs@RSV Biocompatibility
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Venditti, I.; Iucci, G.; Fratoddi, I.; Cipolletti, M.; Montalesi, E.; Marino, M.; Secchi, V.; Battocchio, C. Direct Conjugation of Resveratrol on Hydrophilic Gold Nanoparticles: Structural and Cytotoxic Studies for Biomedical Applications. Nanomaterials 2020, 10, 1898. https://doi.org/10.3390/nano10101898
Venditti I, Iucci G, Fratoddi I, Cipolletti M, Montalesi E, Marino M, Secchi V, Battocchio C. Direct Conjugation of Resveratrol on Hydrophilic Gold Nanoparticles: Structural and Cytotoxic Studies for Biomedical Applications. Nanomaterials. 2020; 10(10):1898. https://doi.org/10.3390/nano10101898
Chicago/Turabian StyleVenditti, Iole, Giovanna Iucci, Ilaria Fratoddi, Manuela Cipolletti, Emiliano Montalesi, Maria Marino, Valeria Secchi, and Chiara Battocchio. 2020. "Direct Conjugation of Resveratrol on Hydrophilic Gold Nanoparticles: Structural and Cytotoxic Studies for Biomedical Applications" Nanomaterials 10, no. 10: 1898. https://doi.org/10.3390/nano10101898