J Appl Biomed 7:163-173, 2009 | DOI: 10.32725/jab.2009.019

Nitric oxide, health and disease

Carlos Kusano Bucalen Ferrari*, Eduardo Luzia França, Adenilda Cristina Honorio-França
Biomedical Research Group, "Campus Universitário do Araguaia", Universidade Federal de Mato Grosso, Brazil

Nitric oxide is a gaseous substance which possesses many important physiological characteristics ranging from its action as a natural immune mechanism to endothelial control of blood pressure. However, it can also generate nitrogen reactive species (peroxynitrite and others), which are involved as a cause of or a consequence of many diseases. This article updates and summarizes the physiological and pathophysiological roles of nitric oxide.

Keywords: peroxynitrite; cancer; cardiovascular diseases; phagocytosis; diabetes mellitus; infection

Received: June 4, 2009; Revised: August 5, 2009; Published: July 31, 2009  Show citation

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Ferrari CKB, Luzia França E, Honorio-França AC. Nitric oxide, health and disease. J Appl Biomed. 2009;7(4):163-173. doi: 10.32725/jab.2009.019.
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