Abstract
Objective:
This study investigated the association between fragmented QRS and the severity
of carotid artery disease.
Materials
and Methods: 168 patients who underwent carotid
angiography due to transient ischemic attack or ischemic stroke between March
2009 and July 2017 were enrolled in the study. Patients enrolled in the study
were divided into two groups according to severity of carotid artery disease on
carotid angiography. Group One consisted of patients with a carotid stenosis of
<50% (n:82) and group 2 consisted of patients with a carotid stenosis of
≥50% (n:86). Two groups were compared in terms of existence of fragmented QRS on
electrocardiogram prior to carotid endarterectomy by using hospital records.
Results:
The
study group consisted of 168 patients. Group One showed more male predominance
and this indicated a significant difference in terms of gender between two
groups (p=0.026). Existence of chronic obstructive pulmonary disease was more
common in group 2 and this indicated a statistically significant difference
(p=0.001). 12-lead ECG of patients in group 2 tended to demonstrate fQRS much
frequently compared to patients in group 1 (p=0.002).
Conclusion:
fQRS seems to be associated with the severity of CAD and assessment of fQRS can
be a predictive factor to determine high risk patients for concealed coronary
artery disease in patients with severe carotid artery disease and without a
history of coronary artery disease.
References
- 1- Bhatt DL, Eagle KA, Ohman EM, Hirsch AT, Goto S, Mahoney EM, et al. Comparative determinants of 4-year cardiovascular event rates in stable outpatients at risk of or with atherothrombosis. JAMA 2010;304:1350e1357.
- 2- Basaran Y, Tigen K, Karaahmet T, Isiklar I, Cevik C, Gurel E, et al. Fragmented QRS complexes are associated with cardiac fibrosis and significant intraventricular systolic dyssynchrony in nonischemic dilated cardiomyopathy patients with a narrow QRS interval. Echocardiography 2011;28(1):62–68.
- 3- Das MK, Saha C, El Masry H, Peng J, Dandamudi G, Mahenthiran J, et al. Fragmented QRS on a 12-lead ECG: A predictor of mortality and cardiac events in patients with coronary artery disease. Heart Rhythm 2007;4:1385–1392.
- 4- Chatterjee S, Changawala N. Fragmented QRS complex: A novel marker of cardiovascular disease. Clin Cardiol 2010;33:68–71
- 5- Das MK, Maskoun W, Shen C, Michael MA, Suradi H, Desai M, et al. Fragmented QRS on twelve-lead electrocardiogram predicts arrhythmic events in patients with ischemic and nonischemic cardiomyopathy. Heart Rhythm 2010;7:74–80.
- 6- Canpolat U, Kabakci G, Aytemir K, Dural M, Sahiner L, Yorgun H, et al. Fragmented QRS complex predicts the arrhythmic events in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. J Cardiovasc Electrophysiol 2013;24:1260–1266.
- 7- Wang J, Tang M, Mao KX, Chu JM, Hua W, Jia YH, et al. Idiopathic ventricular fibrillation with fragmented QRS complex and J wave in resting electrocardiogram. J Geriatr Cardiol 2012;9:143– 147.
- 8- Godet G, Riou B, Bertrand M, Fle´ron MH, Goarin JP, Montalescot G, et al. Does preoperative coronary angioplasty improve postoperative cardiac outcome? Anesthesiology 2005;102:739e46.
- 9- Sprung J, Abdelmalak B, Gottlieb A, Mayhew C, Hammel J, Levy PJ, et al. Analysis of risk factors for myocardial infarction and cardiac mortality after major vascular surgery. Anesthesiology 2000;93:129e40.
- 10- Brilakis ES, Orford JL, Fasseas P, Wilson SH, Melby S, Lennon RJ, et al. Outcome of patients undergoing balloon angioplasty in the two months prior to noncardiac surgery. Am J Cardiol 2005; 96:512e4
- 11- Rihal CS, Eagle KA, Mickel MC, Foster ED, Sopko G, Gersh BJ. Surgical therapy for coronary artery disease among patients with combined coronary artery and peripheral vascular disease. Circulation 1995;91:46e53.
- 12- Jung JL, Jae HL, Jin WJ, Jun YC. Fragmented QRS and abnormal creatine kinase-MB are predictors of coronary artery disease in patients with angina and normal electrocardiographs. Korean J Intern Med 2017;32:469-477
- 13- Korkmaz A, Yildiz A, Demir M, Ozyazgan B, Sahan E, Acar B, et al. The relationship between fragmented QRS and functional significance of coronary lesions. J Electrocardiol. 2017 May - Jun;50(3):282-286.
Abstract
Amaç: Bu
çalışmada fragmente QRS ile karotis arter hastalığının ciddiyeti arasındaki
ilişki araştırılmıştır.
Gereç
ve Yöntemler: Mart 2009 ve Temmuz 2017 tarihleri arasında
geçici iskemik atak veya iskemik inme nedeni karotis anjiyografi uygulanan 168
hasta çalışmaya dahil edldi. Çalışmaya dahil edilen hastalar karotis
anjiyografideki karotis arter hastalığının ciddiyetine göre 2 sınıfa ayrıldı.
İlk grupta karotis darlığı %50’nin altında olan hastalar var iken (n:82) ikinci
grupta karotis darlığı ≥%50 olan hastalardan oluşmaktaydı (n:86). İki grup
karotis endarterektomi ameliyatı öncesi elektrokardiyogramları taranarak fragmente
QRS varlığı açısından karşılaştırıldı.
Bulgular:
Çalışma
populasyonu toplam 168 hastadan oluşmaktaydı. Birinci grupta erkek cinsiyet
hakimdi ve bu istatistiksel olarak anlamlı idi (p=0.026). Kronik obstruktif
akciğer hatslığı ise ikinci grupta daha fazla idi ve bu istatistiksel olarak
anlamlı idi (p=0.001). İkinci gruptaki hastaların 12 derivasyonlu elektrokardiyogramlarında
fragmente QRS varlığı birinci gruba kıyasla istatistiksel olarak daha fazla idi
(p=0.002).
Sonuç: Fragmente
QRS varlığı karotis arter hastalığının ciddiyeti ile ilişkili görünmektedir. Fragmente
QRS değerlendirilmesi ciddi karotis arter hastalığına sahip olup tanısı
konmamış latent koroner arter hastalığı olan hastaların saptanmasını tahmin
ettirici bir faktör olarak kullanılabilir.
References
- 1- Bhatt DL, Eagle KA, Ohman EM, Hirsch AT, Goto S, Mahoney EM, et al. Comparative determinants of 4-year cardiovascular event rates in stable outpatients at risk of or with atherothrombosis. JAMA 2010;304:1350e1357.
- 2- Basaran Y, Tigen K, Karaahmet T, Isiklar I, Cevik C, Gurel E, et al. Fragmented QRS complexes are associated with cardiac fibrosis and significant intraventricular systolic dyssynchrony in nonischemic dilated cardiomyopathy patients with a narrow QRS interval. Echocardiography 2011;28(1):62–68.
- 3- Das MK, Saha C, El Masry H, Peng J, Dandamudi G, Mahenthiran J, et al. Fragmented QRS on a 12-lead ECG: A predictor of mortality and cardiac events in patients with coronary artery disease. Heart Rhythm 2007;4:1385–1392.
- 4- Chatterjee S, Changawala N. Fragmented QRS complex: A novel marker of cardiovascular disease. Clin Cardiol 2010;33:68–71
- 5- Das MK, Maskoun W, Shen C, Michael MA, Suradi H, Desai M, et al. Fragmented QRS on twelve-lead electrocardiogram predicts arrhythmic events in patients with ischemic and nonischemic cardiomyopathy. Heart Rhythm 2010;7:74–80.
- 6- Canpolat U, Kabakci G, Aytemir K, Dural M, Sahiner L, Yorgun H, et al. Fragmented QRS complex predicts the arrhythmic events in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. J Cardiovasc Electrophysiol 2013;24:1260–1266.
- 7- Wang J, Tang M, Mao KX, Chu JM, Hua W, Jia YH, et al. Idiopathic ventricular fibrillation with fragmented QRS complex and J wave in resting electrocardiogram. J Geriatr Cardiol 2012;9:143– 147.
- 8- Godet G, Riou B, Bertrand M, Fle´ron MH, Goarin JP, Montalescot G, et al. Does preoperative coronary angioplasty improve postoperative cardiac outcome? Anesthesiology 2005;102:739e46.
- 9- Sprung J, Abdelmalak B, Gottlieb A, Mayhew C, Hammel J, Levy PJ, et al. Analysis of risk factors for myocardial infarction and cardiac mortality after major vascular surgery. Anesthesiology 2000;93:129e40.
- 10- Brilakis ES, Orford JL, Fasseas P, Wilson SH, Melby S, Lennon RJ, et al. Outcome of patients undergoing balloon angioplasty in the two months prior to noncardiac surgery. Am J Cardiol 2005; 96:512e4
- 11- Rihal CS, Eagle KA, Mickel MC, Foster ED, Sopko G, Gersh BJ. Surgical therapy for coronary artery disease among patients with combined coronary artery and peripheral vascular disease. Circulation 1995;91:46e53.
- 12- Jung JL, Jae HL, Jin WJ, Jun YC. Fragmented QRS and abnormal creatine kinase-MB are predictors of coronary artery disease in patients with angina and normal electrocardiographs. Korean J Intern Med 2017;32:469-477
- 13- Korkmaz A, Yildiz A, Demir M, Ozyazgan B, Sahan E, Acar B, et al. The relationship between fragmented QRS and functional significance of coronary lesions. J Electrocardiol. 2017 May - Jun;50(3):282-286.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Articles |
| Authors | |
| Publication Date | June 29, 2018 |
| Submission Date | January 13, 2018 |
| Published in Issue | Year 2018 Volume: 8 Issue: 2 |
Cited By
Şizofreni Hastalarında Brugada EKG Paterni ve Fragmente QRS İlişkisi
Sakarya Medical Journal
Osman BEKTAŞ
https://doi.org/10.31832/smj.792890
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