Proceedings of the International Conference on Sustainable Innovation on Health Sciences and Nursing (ICOSI-HSN 2022)

Saliva as Diagnostic Medium to Detect Infectious Disease in Human Body: A Review

Authors
Dian Yosi Arinawati1, *, Mitha Novianti1
1Universitas Muhammadiyah Yogyakarta, Special Region of Yogyakarta 55183, Kasihan, Indonesia
*Corresponding author. Email: dianyosi@umy.ac.id
Corresponding Author
Dian Yosi Arinawati
Available Online 26 December 2022.
DOI
10.2991/978-94-6463-070-1_50How to use a DOI?
Keywords
bacterial; fungal; infection; saliva; viral
Abstract

Saliva is a oral biological fluid that has many benefits and has an function for maintaining oral health and can be clinically informative as a diagnostic media. Biomarkers in saliva are molecules that contain certain ingredients can be used to diagnose disease or assess the development and outcome of treatment. The characteristics of biomarkers make it feasible to be an alternative diagnostic media. The latest emerging technology has revealed medically that salivary biomarkers are important for detection many disease conditions such as cancer, viruses, bacteria, cardiac disease, autoimmune and metabolism disturbance. The purpose of this study is to determine the role of saliva as a diagnostic medium through its various biomarkers in saliva that can detect diseases caused by viral, bacterial and fungal infections in the body. This literature review of PubMed database was conducted without any limitation on date of publication to identify the potential of saliva as diagnostic medium of infectious diseases. Saliva has potential as medium diagnostic for ZIKA virus in the early week of symptom onset. High level of IgG can be detected in saliva of Helicobacter pylori bacterial infection in the body. Changes in salivary proteins such as calprotectin and histatin also have important diagnostic values in the detection of fungal infections. It can be concluded that saliva has potential as diagnostic medium that can be used in detecting various diseases caused by viral, bacterial and fungal infections.

Copyright
© 2022 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International Conference on Sustainable Innovation on Health Sciences and Nursing (ICOSI-HSN 2022)
Series
Advances in Health Sciences Research
Publication Date
26 December 2022
ISBN
10.2991/978-94-6463-070-1_50
ISSN
2468-5739
DOI
10.2991/978-94-6463-070-1_50How to use a DOI?
Copyright
© 2022 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - Dian Yosi Arinawati
AU  - Mitha Novianti
PY  - 2022
DA  - 2022/12/26
TI  - Saliva as Diagnostic Medium to Detect Infectious Disease in Human Body: A Review
BT  - Proceedings of the International Conference on Sustainable Innovation on Health Sciences and Nursing (ICOSI-HSN 2022)
PB  - Atlantis Press
SP  - 395
EP  - 404
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-070-1_50
DO  - 10.2991/978-94-6463-070-1_50
ID  - Arinawati2022
ER  -