Paget´s disease of bone in a patient on peritoneal dialysis

Paget´s disease of bone in a patient on peritoneal dialysis

Flores-Padilla Guillermo^1,2, Solis Jose Gabriel^1,3*, Zavala-Jonguitud Luis Fernando^1,4, Juarez-Villa Daniel^1,5, Olascoaga-Lugo Arturo^1,6

¹Department of Internal Medicine, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social. México City, México. Adress: Avenida Cuauhtémoc # 330 Colonia Doctores. Alcaldía Cuauhtémoc. Ciudad de México 06725. México. ²ORCID ID: https://orcid.org/0000-0003-0697-620X ³ORCID ID: https://orcid.org/0000-0003-3532-6062 ⁴ORCID ID: https://orcid.org/0000-0002-6405-7810 ⁵ORCID ID: https://orcid.org/0000-0002-6462-8935 ⁶ORCID ID: https://orcid.org/0000-0002-6557-7180

Paget´s disease of bone is a disorder characterized by disorganized bone remodeling. It´s occurrence in patients with end-stage kidney disease on renal replacement therapy is rare. Here we report a case of Paget´s disease of bone in an 80-year-old male on peritoneal dialysis that presented a high level of alkaline-phosphatase with a mildly elevated parathyroid hormone level and typical imaging findings localized to the pelvis. This is the fourth reported case of Paget´s disease in a patient on peritoneal dialysis and the first treated with denosumab.

Keywords: Paget disease of bone; kidney failure; peritoneal dialysis; denosumab

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How to cite this article:

Flores-Padilla Guillermo, Solis Jose Gabriel, Zavala-Jonguitud Luis Fernando, Juarez-Villa Daniel, Olascoaga-Lugo Arturo. Paget´s disease of bone in a patient on peritoneal dialysis. International Journal of Case Reports, 2021; 5:196. DOI: 10.28933/ijcr-2021-01-2205

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