A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina
Posted on 2020-03-13 - 12:08
A new chlorinated phenolic compound, methyl-3-chloro-2-hydroxy-4-methoxy-6-pentylbenzoate (1) and 4 known compounds (2-5) were isolated from the Antarctic lichen, Pertusaria dactylina (Pertusariaceae). The structure of the new compound was determined by means of One-dimensional and two dimensional nuclear magnetic resonance (1D and 2D NMR) and high-resolution fast atom bombardment mass spectrometry (HRFABMS) experiments. The antimicrobial activities of compounds 1 to 5 against Staphylococcus aureus and Candida albicans were evaluated. The results showed that compound 1 exhibited a weak inhibitory effect against C. albicans with an IC50 value of 67 ± 7 μg/mL.
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Koo, Man H.; Kim, Min J.; Seo, Jae E.; Kim, Ji H.; Han, Se J.; Kim, Il C.; et al. (2020). A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina. SAGE Journals. Collection. https://doi.org/10.25384/SAGE.c.4893264.v1
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AUTHORS (8)
MK
Man H. Koo
MK
Min J. Kim
JS
Jae E. Seo
JK
Ji H. Kim
SH
Se J. Han
IK
Il C. Kim
JL
Jun H. Lee
UY
Ui J. Youn