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BY-NC-ND 3.0 license Open Access Published by De Gruyter Open Access June 9, 2013

Non-invasive brain stimulation in children: Applications and future directions

  • Thilinie Rajapakse EMAIL logo and Adam Kirton

Abstract

Transcranial magnetic stimulation (TMS) is a neurostimulation and neuromodulation technique that has provided over two decades of data in focal, non-invasive brain stimulation based on the principles of electromagnetic induction. Its minimal risk, excellent tolerability and increasingly sophisticated ability to interrogate neurophysiology and plasticity make it an enviable technology for use in pediatric research with future extension into therapeutic trials. While adult trials show promise in using TMS as a novel, non-invasive, non-pharmacologic diagnostic and therapeutic tool in a variety of nervous system disorders, its use in children is only just emerging. TMS represents an exciting advancement to better understand and improve outcomes from disorders of the developing brain.

[1] Wassermann E.M., Epstein C.M., Ziemann U. (Eds.) The Oxford handbook of transcranial stimulation, Oxford University Press, New York, 2008 Search in Google Scholar

[2] Rossi S., Hallett M., Rossini P.M., Pascual-Leone A., Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research, Clin. Neurophysiol., 2009, 120, 2008–2039 http://dx.doi.org/10.1016/j.clinph.2009.08.01610.1016/j.clinph.2009.08.016Search in Google Scholar

[3] Garvey M.A., Mall V., Transcranial magnetic stimulation in children, Clin. Neurophysiol. 2008, 119, 973–984 http://dx.doi.org/10.1016/j.clinph.2007.11.04810.1016/j.clinph.2007.11.048Search in Google Scholar

[4] Frye R.E., Rotenberg A., Ousley M., Pascual-Leone A., Transcranial magnetic stimulation in child neurology: current and future directions, J. Child Neurol., 2008, 23, 79–96 http://dx.doi.org/10.1177/088307380730797210.1177/0883073807307972Search in Google Scholar

[5] Gilbert D.L., Garvey M.A., Bansal A.S., Lipps T., Zhang J., Wassermann E.M., Should transcranial magnetic stimulation research in children be considered minimal risk?, Clin. Neurophysiol. 2004, 115, 1730–1739 http://dx.doi.org/10.1016/j.clinph.2003.10.03710.1016/j.clinph.2003.10.037Search in Google Scholar

[6] McCreery D.B., Agnew W.F., Yuen T.G., Bullara L., Charge density and charge per phase as cofactors in neural injury induced by electrical stimulation, IEEE Trans. Biomed. Eng., 1990, 37, 996–1001 http://dx.doi.org/10.1109/10.10281210.1109/10.102812Search in Google Scholar

[7] Lisanby S.H., Belmaker R.H., Animal models of the mechanisms of action of repetitive transcranial magnetic stimulation (RTMS): comparisons with electroconvulsive shock (ECS), Depress. Anxiety, 2000, 12, 178–187 http://dx.doi.org/10.1002/1520-6394(2000)12:3<178::AID-DA10>3.0.CO;2-N10.1002/1520-6394(2000)12:3<178::AID-DA10>3.0.CO;2-NSearch in Google Scholar

[8] Ghaziuddin N., Dumas S., Hodges E., Use of continuation or maintenance electroconvulsive therapy in adolescents with severe treatment-resistant depression, J. ECT, 2011, 27, 168–174 http://dx.doi.org/10.1097/YCT.0b013e3181f665e410.1097/YCT.0b013e3181f665e4Search in Google Scholar

[9] Garvey M.A., Gilbert D.L., Transcranial magnetic stimulation in children, Eur. J. Paediatr. Neurol. 2004, 8, 7–19 http://dx.doi.org/10.1016/j.ejpn.2003.11.00210.1016/j.ejpn.2003.11.002Search in Google Scholar

[10] Quintana H., Transcranial magnetic stimulation in persons younger than the age of 18, J. ECT, 2005, 21, 88–95 http://dx.doi.org/10.1097/01.yct.0000162556.02720.5810.1097/01.yct.0000162556.02720.58Search in Google Scholar

[11] Duque J., Hummel F., Celnik P., Murase N., Mazzocchio R., Cohen L.G., Transcallosal inhibition in chronic subcortical stroke, Neuroimage, 2005, 28, 940–946 http://dx.doi.org/10.1016/j.neuroimage.2005.06.03310.1016/j.neuroimage.2005.06.033Search in Google Scholar

[12] Takeuchi N., Chuma T., Matsuo Y., Watanabe I., Ikoma K., Repetitive transcranial magnetic stimulation of contralesional primary motor cortex improves hand function after stroke, Stroke, 2005, 36, 2681–2686 http://dx.doi.org/10.1161/01.STR.0000189658.51972.3410.1161/01.STR.0000189658.51972.34Search in Google Scholar PubMed

[13] Khedr E.M., Ahmed M.A., Fathy N., Rothwell J.C., Therapeutic trial of repetitive transcranial magnetic stimulation after acute ischemic stroke, Neurology, 2005, 65, 466–468 http://dx.doi.org/10.1212/01.wnl.0000173067.84247.3610.1212/01.wnl.0000173067.84247.36Search in Google Scholar PubMed

[14] Naeser M.A., Martin P.I., Nicholas M., Baker E.H., Seekins H., Kobayashi M., et al., Improved picture naming in chronic aphasia after TMS to part of right Broca’s area: an open-protocol study, Brain Lang., 2005, 93, 95–105 http://dx.doi.org/10.1016/j.bandl.2004.08.00410.1016/j.bandl.2004.08.004Search in Google Scholar PubMed

[15] Mansur C.G., Fregni F., Boggio P.S., Riberto M., Galluci-Neto J., Santos C.M., et al. A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients, Neurology, 2005, 64, 1802–1804 http://dx.doi.org/10.1212/01.WNL.0000161839.38079.9210.1212/01.WNL.0000161839.38079.92Search in Google Scholar PubMed

[16] Hummel F., Cohen L.G., Improvement of motor function with noninvasive cortical stimulation in a patient with chronic stroke, Neurorehabil. Neural Repair, 2005, 19, 14–19 http://dx.doi.org/10.1177/154596830427269810.1177/1545968304272698Search in Google Scholar PubMed

[17] Staudt M., Gerloff C., Grodd W., Holthausen H., Niemann G., Krageloh-Mann I., Reorganization in congenital hemiparesis acquired at different gestational ages, Ann. Neurol., 2004, 56, 854–863 http://dx.doi.org/10.1002/ana.2029710.1002/ana.20297Search in Google Scholar PubMed

[18] Maegaki Y., Maeoka Y., Ishii S., Shiota M., Takeuchi A., Yoshino K., et al., Mechanisms of central motor reorganization in pediatric hemiplegic patients, Neuropediatrics, 1997, 28, 168–174 http://dx.doi.org/10.1055/s-2007-97369510.1055/s-2007-973695Search in Google Scholar PubMed

[19] Salimi I., Martin J.H., Rescuing transient corticospinal terminations and promoting growth with corticospinal stimulation in kittens, J. Neurosci., 2004, 24, 4952–4961 http://dx.doi.org/10.1523/JNEUROSCI.0004-04.200410.1523/JNEUROSCI.0004-04.2004Search in Google Scholar PubMed PubMed Central

[20] Valero-Cabre A., Rushmore R.J., Payne B.R., Low frequency transcranial magnetic stimulation on the posterior parietal cortex induces visuotopically specific neglect-like syndrome, Exp. Brain Res., 2006, 1–8 10.1007/s00221-005-0307-4Search in Google Scholar PubMed

[21] Valero-Cabre A., Payne B.R., Rushmore J., Lomber S.G., Pascual-Leone A., Impact of repetitive transcranial magnetic stimulation of the parietal cortex on metabolic brain activity: a 14C–2DG tracing study in the cat, Exp. Brain Res., 2005, 163, 1–12 http://dx.doi.org/10.1007/s00221-004-2140-610.1007/s00221-004-2140-6Search in Google Scholar PubMed

[22] Bolay H., Gursoy-Ozdemir Y., Unal I., Dalkara T., Altered mechanisms of motor-evoked potential generation after transient focal cerebral ischemia in the rat: implications for transcranial magnetic stimulation, Brain Res., 2000, 873, 26–33 http://dx.doi.org/10.1016/S0006-8993(00)02466-510.1016/S0006-8993(00)02466-5Search in Google Scholar

[23] Plautz E.J., Barbay S., Frost S.B., Friel K.M., Dancause N., Zoubina E. V., et al., Post-infarct cortical plasticity and behavioral recovery using concurrent cortical stimulation and rehabilitative training: a feasibility study in primates, Neurol. Res., 2003, 25, 801–810 http://dx.doi.org/10.1179/01616410377195388010.1179/016164103771953880Search in Google Scholar

[24] Eyre J.A., Flecknell P.A., Kenyon B.R., Koh T.H., Miller S., Acute effects of electromagnetic stimulation of the brain on cortical activity, cortical blood flow, blood pressure and heart rate in the cat: an evaluation of safety, J. Neurol. Neurosurg. Psychiatry, 1990, 53, 507–513 http://dx.doi.org/10.1136/jnnp.53.6.50710.1136/jnnp.53.6.507Search in Google Scholar

[25] Edgley S.A., Eyre J.A., Lemon R.N., Miller S., Excitation of the corticospinal tract by electromagnetic and electrical stimulation of the scalp in the macaque monkey, J. Physiol., 1990, 425, 301–320 10.1113/jphysiol.1990.sp018104Search in Google Scholar

[26] Wassermann E.M., Risk and safety of repetitive transcranial magnetic stimulation: report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5–7, 1996, Electroencephalogr. Clin. Neurophysiol., 1998, 108, 1–16 http://dx.doi.org/10.1016/S0168-5597(97)00096-810.1016/S0168-5597(97)00096-8Search in Google Scholar

[27] Theodore W.H., Hunter K., Chen R., Vega-Bermudez F., Boroojerdi B., Reeves-Tyer P., et al. Transcranial magnetic stimulation for the treatment of seizures: a controlled study, Neurology, 2002, 59, 560–562 http://dx.doi.org/10.1212/WNL.59.4.56010.1212/WNL.59.4.560Search in Google Scholar

[28] Tassinari C.A., Cincotta M., Zaccara G., Michelucci R., Transcranial magnetic stimulation and epilepsy, Clin. Neurophysiol., 2003, 114, 777–798 http://dx.doi.org/10.1016/S1388-2457(03)00004-X10.1016/S1388-2457(03)00004-XSearch in Google Scholar

[29] Pascual-Leone A., Valls-Sole J., Wassermann E.M., Brasil-Neto J., Cohen L.G., Hallett M., Effects of focal transcranial magnetic stimulation on simple reaction time to acoustic, visual and somatosensory stimuli, Brain, 1992, 115, 1045–1059 http://dx.doi.org/10.1093/brain/115.4.104510.1093/brain/115.4.1045Search in Google Scholar

[30] Collado-Corona M.A., Mora-Magana I., Cordero G.L., et al., Transcranial magnetic stimulation and acoustic trauma or hearing loss in children, Neurol. Res., 2001, 23, 343–346 http://dx.doi.org/10.1179/01616410110119853210.1179/016164101101198532Search in Google Scholar

[31] Kirton A., Chen R., Friefeld S., Gunraj C., Pontigon A.M., deVeber G., Contralesional repetitive transcranial magnetic stimulation for chronic hemiparesis in subcortical paediatric stroke: a randomised trial, Lancet Neurol., 2008, 7, 507–513 http://dx.doi.org/10.1016/S1474-4422(08)70096-610.1016/S1474-4422(08)70096-6Search in Google Scholar

[32] Kirton A., deVeber G., Gunraj C., Chen R., Neurocardiogenic syncope complicating pediatric transcranial magnetic stimulation, Pediatr. Neurol., 2008, 39, 196–197 http://dx.doi.org/10.1016/j.pediatrneurol.2008.06.00410.1016/j.pediatrneurol.2008.06.004Search in Google Scholar

[33] Rossini P.M., Desiato M.T., Caramia M.D., Age-related changes of motor evoked potentials in healthy humans: non-invasive evaluation of central and peripheral motor tracts excitability and conductivity, Brain Res., 1992, 593, 14–19 http://dx.doi.org/10.1016/0006-8993(92)91256-E10.1016/0006-8993(92)91256-ESearch in Google Scholar

[34] Lin K.L., Pascual-Leone A., Transcranial magnetic stimulation and its applications in children, Chang Gung Med. J., 2002, 25, 424–436 Search in Google Scholar

[35] Rajapakse T., Damji O.K., Safety and tolerability of Transcranial Magnetic Stimulation (TMS) neurophysiology and interventional rTMS in children with perinatal stroke, 16th Annual Meeting of the North American Neuromodulation Society, 2012, 11 Search in Google Scholar

[36] Liebetanz D., Fauser S., Michaelis T., Czéh B., Watanabe T., Paulus W., et al., Safety aspects of chronic low-frequency transcranial magnetic stimulation based on localized proton magnetic resonance spectroscopy and histology of the rat brain, J. Psychiatr. Res., 2003, 37, 277–286 http://dx.doi.org/10.1016/S0022-3956(03)00017-710.1016/S0022-3956(03)00017-7Search in Google Scholar

[37] Garvey M.A., Kaczynski K.J., Becker D.A., Bartko J.J., Subjective reactions of children to single-pulse transcranial magnetic stimulation, J. Child. Neurol., 2001, 16, 891–894 http://dx.doi.org/10.1177/08830738010160120510.1177/088307380101601205Search in Google Scholar PubMed

[38] Sokhadze E.M., Baruth J.M., Sears L., Sokhadze G.E., El-Baz A.S., Casanova M.F., Prefrontal neuromodulation using rTMS improves error monitoring and correction function in autism, Appl. Psychophysiol. Biofeedback, 2012, 37, 91–102 http://dx.doi.org/10.1007/s10484-012-9182-510.1007/s10484-012-9182-5Search in Google Scholar PubMed

[39] Croarkin P.E., Wall C.A., Nakonezny P.A., Buyukdura J.S., Husain M.M., Sampson S.M., et al., Increased cortical excitability with prefrontal high-frequency repetitive transcranial magnetic stimulation in adolescents with treatment-resistant major depressive disorder, J. Child Adolesc. Psychopharmacol., 2012, 22, 56–64 http://dx.doi.org/10.1089/cap.2011.005410.1089/cap.2011.0054Search in Google Scholar PubMed

[40] Enticott P.G., Rinehart N.J., Tonge B.J., Bradshaw J.L., Fitzgerald P.B., Repetitive transcranial magnetic stimulation (rTMS) improves movement-related cortical potentials in autism spectrum disorders, Brain Stimul., 2012, 5, 30–37 http://dx.doi.org/10.1016/j.brs.2011.02.00110.1016/j.brs.2011.02.001Search in Google Scholar PubMed

[41] Wall C.A., Croarkin P.E., Sim L.A., Husain M.M., Janicak P.G., Kozel F.A., et al., Adjunctive use of repetitive transcranial magnetic stimulation in depressed adolescents: a prospective, open pilot study, J. Clin. Psychiatry, 2011, 72, 1263–1269 http://dx.doi.org/10.4088/JCP.11m0700310.4088/JCP.11m07003Search in Google Scholar PubMed

[42] Kwon H.J., Lim W.S., Lim M.H., Lee S.J., Hyun J.K., Chae J.H., et al., 1-Hz low frequency repetitive transcranial magnetic stimulation in children with Tourette’s syndrome, Neurosci. Lett., 2011, 492, 1–4 http://dx.doi.org/10.1016/j.neulet.2011.01.00710.1016/j.neulet.2011.01.007Search in Google Scholar PubMed

[43] Hu S.H., Wang S.S., Zhang M.M., Wang J.W., Hu J.B., Huang M.L., et al., Repetitive transcranial magnetic stimulation-induced seizure of a patient with adolescent-onset depression: a case report and literature review, J. Int. Med. Res., 2011, 39, 2039–2044 http://dx.doi.org/10.1177/14732300110390055210.1177/147323001103900552Search in Google Scholar PubMed

[44] Sun W., Fu W., Mao W., Wang D., Wang Y., Low-frequency repetitive transcranial magnetic stimulation for the treatment of refractory partial epilepsy, Clin. EEG Neurosci., 2011, 42, 40–44 http://dx.doi.org/10.1177/15500594110420010910.1177/155005941104200109Search in Google Scholar PubMed

[45] Kirton A., deVeber G., Gunraj C., Chen R., Cortical excitability and interhemispheric inhibition after subcortical pediatric stroke: plastic organization and effects of rTMS, Clin. Neurophysiol., 2010, 121, 1922–1929 http://dx.doi.org/10.1016/j.clinph.2010.04.02110.1016/j.clinph.2010.04.021Search in Google Scholar PubMed

[46] Sokhadze E., Baruth J., Tasman A., Mansoor M., Ramaswamy R., Sears L., et al., Low-frequency repetitive transcranial magnetic stimulation (rTMS) affects event-related potential measures of novelty processing in autism, Appl. Psychophysiol. Biofeedback, 2010, 35, 147–161 http://dx.doi.org/10.1007/s10484-009-9121-210.1007/s10484-009-9121-2Search in Google Scholar PubMed PubMed Central

[47] Mylius V., Gerstner A., Peters M., Prokisch H., Leonhardt A., Hellwig D., et al., Low-frequency rTMS of the premotor cortex reduces complex movement patterns in a patient with pantothenate kinaseassociated neurodegenerative disease (PKAN), Neurophysiol. Clin., 2009, 39, 27–30 http://dx.doi.org/10.1016/j.neucli.2008.12.00310.1016/j.neucli.2008.12.003Search in Google Scholar PubMed

[48] Sokhadze E.M., El-Baz A., Baruth J., Mathai G., Sears L., Casanova M.F., Effects of low frequency repetitive transcranial magnetic stimulation (rTMS) on gamma frequency oscillations and event-related potentials during processing of illusory figures in autism, J. Autism Dev. Disord., 2009, 39, 619–634 http://dx.doi.org/10.1007/s10803-008-0662-710.1007/s10803-008-0662-7Search in Google Scholar PubMed

[49] Rotenberg A., Bae E.H., Takeoka M., Tormos J.M., Schachter S.C., Pascual-Leone A., Repetitive transcranial magnetic stimulation in the treatment of epilepsia partialis continua, Epilepsy Search in Google Scholar

[50] Jardri R., Delevoye-Turrell Y., Lucas B., Pins D., Bulot V., Delmaire C., et al., Clinical practice of rTMS reveals a functional dissociation between agency and hallucinations in schizophrenia, Neuropsychologia, 2009, 47, 132–138 http://dx.doi.org/10.1016/j.neuropsychologia.2008.08.00610.1016/j.neuropsychologia.2008.08.006Search in Google Scholar PubMed

[51] Jardri R., Lucas B., Delevoye-Turrell Y., Delmaire C., Delion P., Thomas P., et al., An 11-year-old boy with drug-resistant schizophrenia treated with temporo-parietal rTMS, Mol. Psychiatry, 2007, 12, 320 http://dx.doi.org/10.1038/sj.mp.400196810.1038/sj.mp.4001968Search in Google Scholar PubMed

[52] Bloch Y., Grisaru N., Harel E.V., Beitler G., Faivel N., Ratzoni G., et al., Repetitive transcranial magnetic stimulation in the treatment of depression in adolescents: an open-label study, J. ECT, 2008, 24, 156–159 http://dx.doi.org/10.1097/YCT.0b013e318156aa4910.1097/YCT.0b013e318156aa49Search in Google Scholar PubMed

[53] Rotenberg A., Positario-Cabacar D., Bae E.H., Harini C., Pascual-Leone A., Takeoka M., Transient suppression of seizures by repetitive transcranial magnetic stimulation in a case of Rasmussen’s encephalitis, Epilepsy Behav., 2008, 13, 260–262 http://dx.doi.org/10.1016/j.yebeh.2007.12.02210.1016/j.yebeh.2007.12.022Search in Google Scholar PubMed PubMed Central

[54] Valle A.C., Dionisio K., Pitskel N.B., Pascual-Leone A., Orsati F., Ferreira M.J., et al., Low and high frequency repetitive transcranial magnetic stimulation for the treatment of spasticity, Dev. Med. Child Neurol., 2007, 49, 534–538 http://dx.doi.org/10.1111/j.1469-8749.2007.00534.x10.1111/j.1469-8749.2007.00534.xSearch in Google Scholar PubMed

[55] Fregni F., Boggio P.S., Valle A.C., Otachi P., Thut G., Rigonatti S.P., et al., Homeostatic effects of plasma valproate levels on corticospinal excitability changes induced by 1Hz rTMS in patients with juvenile myoclonic epilepsy, Clin. Neurophysiol., 2006, 117, 1217–1227 http://dx.doi.org/10.1016/j.clinph.2006.02.01510.1016/j.clinph.2006.02.015Search in Google Scholar

[56] Loo C., McFarquhar T., Walter G., Transcranial magnetic stimulation in adolescent depression, Australas. Psychiatry, 2006, 14, 81–85 10.1111/j.1440-1665.2006.02251.xSearch in Google Scholar

[57] Morales O.G., Henry M.E., Nobler M.S., Wassermann E.M., Lisanby S.H., Electroconvulsive therapy and repetitive transcranial magnetic stimulation in children and adolescents: a review and report of two cases of epilepsia partialis continua, Child Adolesc. Psychiatr. Clin. N. Am., 2005, 14, 193–210 http://dx.doi.org/10.1016/j.chc.2004.07.01010.1016/j.chc.2004.07.010Search in Google Scholar

[58] Graff-Guerrero A., Gonzáles-Olvera J., Ruiz-García M., Avila-Ordoñez U., Vaugier V., García-Reyna J.C., rTMS reduces focal brain hyperperfusion in two patients with EPC, Acta Neurol. Scand., 2004, 109, 290–296 http://dx.doi.org/10.1046/j.1600-0404.2003.00222.x10.1046/j.1600-0404.2003.00222.xSearch in Google Scholar

[59] Eyre J.A., Taylor J.P., Villagra F., Smith M., Miller S., Evidence of activitydependent withdrawal of corticospinal projections during human development, Neurology, 2001, 57, 1543–1554 http://dx.doi.org/10.1212/WNL.57.9.154310.1212/WNL.57.9.1543Search in Google Scholar

[60] Eyre J.A., Smith M., Dabydeen L., Clowry G.J., Petacchi E., Battini R., et al., Is hemiplegic cerebral palsy equivalent to amblyopia of the corticospinal system?, Ann. Neurol., 2007, 62, 493–503 http://dx.doi.org/10.1002/ana.2110810.1002/ana.21108Search in Google Scholar

[61] Garvey M.A., Ziemann U., Bartko J.J., Denckla M.B., Barker C.A., Wassermann E.M., Cortical correlates of neuromotor development in healthy children, Clin. Neurophysiol., 2003, 114, 1662–1670 http://dx.doi.org/10.1016/S1388-2457(03)00130-510.1016/S1388-2457(03)00130-5Search in Google Scholar

[62] Muller K., Ebner B., Homberg V., Maturation of fastest afferent and efferent central and peripheral pathways: no evidence for a constancy of central conduction delays, Neurosci. Lett., 1994, 166, 9–12 http://dx.doi.org/10.1016/0304-3940(94)90828-110.1016/0304-3940(94)90828-1Search in Google Scholar

[63] Abbruzzese G., Trompetto C., Clinical and research methods for evaluating cortical excitability, J. Clin. Neurophysiol., 2002, 19, 307–321 http://dx.doi.org/10.1097/00004691-200208000-0000510.1097/00004691-200208000-00005Search in Google Scholar

[64] Caramia M.D., Desiato M.T., Cicinelli P., Iani C., Rossini P.M., Latency jump of “relaxed” versus “contracted” motor evoked potentials as a marker of cortico-spinal maturation, Electroencephalogr. Clin. Neurophysiol., 1993, 89, 61–66 http://dx.doi.org/10.1016/0168-5597(93)90086-510.1016/0168-5597(93)90086-5Search in Google Scholar

[65] Staudt M., Grodd W., Gerloff C., Erb M., Stitz J., Krageloh-Mann I., Two types of ipsilateral reorganization in congenital hemiparesis: a TMS and fMRI study, Brain, 2002, 125, 2222–2237 http://dx.doi.org/10.1093/brain/awf22710.1093/brain/awf227Search in Google Scholar PubMed

[66] Muller K., Kass-Iliyya F., Reitz M., Ontogeny of ipsilateral corticospinal projections: a developmental study with transcranial magnetic stimulation, Ann. Neurol., 1997, 42, 705–711 http://dx.doi.org/10.1002/ana.41042050610.1002/ana.410420506Search in Google Scholar PubMed

[67] Martin J.H., Lee S.J., Activity-dependent competition between developing corticospinal terminations, Neuroreport, 1999, 10, 2277–2282 http://dx.doi.org/10.1097/00001756-199908020-0001010.1097/00001756-199908020-00010Search in Google Scholar PubMed

[68] Martin J.H., Kably B., Hacking A., Activity-dependent development of cortical axon terminations in the spinal cord and brain stem, Exp. Brain Res., 1999, 125, 184–199 http://dx.doi.org/10.1007/s00221005067310.1007/s002210050673Search in Google Scholar PubMed

[69] Martin J.H., Friel K.M., Salimi I., Chakrabarty S., Activity- and usedependent plasticity of the developing corticospinal system, Neurosci. Biobehav. Rev., 2007, 31, 1125–1135 http://dx.doi.org/10.1016/j.neubiorev.2007.04.01710.1016/j.neubiorev.2007.04.017Search in Google Scholar PubMed PubMed Central

[70] Kirton A., Modeling developmental plasticity after perinatal stroke: defining central therapeutic targets in cerebral palsy, Pediatr. Neurol., 2013, 48, 81–94 http://dx.doi.org/10.1016/j.pediatrneurol.2012.08.00110.1016/j.pediatrneurol.2012.08.001Search in Google Scholar PubMed

[71] Werhahn K.J., Kunesch E., Noachtar S., Benecke R., Classen J., Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans, J. Physiol., 1999, 517, 591–597 http://dx.doi.org/10.1111/j.1469-7793.1999.0591t.x10.1111/j.1469-7793.1999.0591t.xSearch in Google Scholar PubMed PubMed Central

[72] Moll G.H., Heinrich H., Wischer S., Tergau F., Paulus W., Rothenberger A., Motor system excitability in healthy children: developmental aspects from transcranial magnetic stimulation, Electroencephalogr. Clin. Neurophysiol. Suppl., 1999, 51, 243–249 Search in Google Scholar

[73] Ziemann U., TMS and drugs, Clin. Neurophysiol., 2004, 115, 1717–1729 http://dx.doi.org/10.1016/j.clinph.2004.03.00610.1016/j.clinph.2004.03.006Search in Google Scholar PubMed

[74] Mall V., Berweck S., Fietzek U.M., Glocker F. X., Oberhuber U., Walther M., et al., Low level of intracortical inhibition in children shown by transcranial magnetic stimulation, Neuropediatrics, 2004, 35, 120–125 http://dx.doi.org/10.1055/s-2004-81583410.1055/s-2004-815834Search in Google Scholar PubMed

[75] Ziemann U., Muellbacher W., Hallett M., Cohen L.G., Modulation of practice-dependent plasticity in human motor cortex, Brain, 2001, 124, 1171–1181 http://dx.doi.org/10.1093/brain/124.6.117110.1093/brain/124.6.1171Search in Google Scholar PubMed

[76] Heinen F., Glocker F.X., Fietzek U., Meyer B.U., Lucking C.H., Korinthenberg R., Absence of transcallosal inhibition following focal magnetic stimulation in preschool children, Ann. Neurol., 1998, 43, 608–612 http://dx.doi.org/10.1002/ana.41043050810.1002/ana.410430508Search in Google Scholar PubMed

[77] Mineyko A., Kirton A., The black box of perinatal ischemic stroke pathogenesis, J. Child Neurol., 2011, 26, 1154–1162 http://dx.doi.org/10.1177/088307381140831210.1177/0883073811408312Search in Google Scholar PubMed PubMed Central

[78] Kirton A., deVeber G., Advances in perinatal ischemic stroke, Pediatr. Neurol., 2009, 40, 205–214 http://dx.doi.org/10.1016/j.pediatrneurol.2008.09.01810.1016/j.pediatrneurol.2008.09.018Search in Google Scholar PubMed

[79] Kirton A., Modeling developmental plasticity after perinatal stroke: defining central therapeutic targets in cerebral palsy, Pediatr. Neurol., 2013, 48, 81–94 http://dx.doi.org/10.1016/j.pediatrneurol.2012.08.00110.1016/j.pediatrneurol.2012.08.001Search in Google Scholar PubMed

[80] Eyre J.A., Corticospinal tract development and its plasticity after perinatal injury, Neurosci. Biobehav. Rev., 2007, 31, 1136–1149 http://dx.doi.org/10.1016/j.neubiorev.2007.05.01110.1016/j.neubiorev.2007.05.011Search in Google Scholar PubMed

[81] Staudt M., Reorganization of the developing human brain after early lesions, Dev. Med. Child Neurol., 2007, 49, 564 http://dx.doi.org/10.1111/j.1469-8749.2007.00564.x10.1111/j.1469-8749.2007.00564.xSearch in Google Scholar PubMed

[82] Pascual-Leone A., Amedi A., Fregni F., Merabet L.B., The plastic human brain cortex, Annu. Rev. Neurosci., 2005, 28, 377–401 http://dx.doi.org/10.1146/annurev.neuro.27.070203.14421610.1146/annurev.neuro.27.070203.144216Search in Google Scholar PubMed

[83] Pascual-Leone A., Tormos J.M., Keenan J., Tarazona F., Canete C., Catala M.D., Study and modulation of human cortical excitability with transcranial magnetic stimulation, J. Clin. Neurophysiol., 1998, 15, 333–343 http://dx.doi.org/10.1097/00004691-199807000-0000510.1097/00004691-199807000-00005Search in Google Scholar PubMed

[84] Adkins-Muir D.L., Jones T.A., Cortical electrical stimulation combined with rehabilitative training: enhanced functional recovery and dendritic plasticity following focal cortical ischemia in rats, Neurol. Res., 2003, 25, 780–788 http://dx.doi.org/10.1179/01616410377195385310.1179/016164103771953853Search in Google Scholar PubMed

[85] Kleim J.A., Bruneau R., VandenBerg P., MacDonald E., Mulrooney R., Pocock D., Motor cortex stimulation enhances motor recovery and reduces peri-infarct dysfunction following ischemic insult, Neurol. Res., 2003, 25, 789–793 http://dx.doi.org/10.1179/01616410377195386210.1179/016164103771953862Search in Google Scholar PubMed

[86] Teskey G.C., Flynn C., Goertzen C.D., Monfils M.H., Young N.A., Cortical stimulation improves skilled forelimb use following a focal ischemic infarct in the rat, Neurol. Res., 2003, 25, 794–800 http://dx.doi.org/10.1179/01616410377195387110.1179/016164103771953871Search in Google Scholar

[87] Maeda F., Keenan J.P., Tormos J.M., Topka H., Pascual-Leone A., Modulation of corticospinal excitability by repetitive transcranial magnetic stimulation, Clin. Neurophysiol., 2000, 111, 800–805 http://dx.doi.org/10.1016/S1388-2457(99)00323-510.1016/S1388-2457(99)00323-5Search in Google Scholar

[88] Chen R., Classen J., Gerloff C., Celnik P., Wassermann E.M., Hallett M., et al., Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation, Neurology, 1997, 48, 1398–1403 http://dx.doi.org/10.1212/WNL.48.5.139810.1212/WNL.48.5.1398Search in Google Scholar

[89] Lisanby S.H., Gutman D., Luber B., Schroeder C., Sackeim H.A., Sham TMS: intracerebral measurement of the induced electrical field and the induction of motor-evoked potentials, Biol. Psychiatry, 2001, 49, 460–463 http://dx.doi.org/10.1016/S0006-3223(00)01110-010.1016/S0006-3223(00)01110-0Search in Google Scholar

[90] Speer A.M., Benson B.E., Kimbrell T.K., Wassermann E.M., Willis M.W., Herscovitsch P., et al., Opposite effects of high and low frequency rTMS on mood in depressed patients: relationship to baseline cerebral activity on PET, J. Affect. Disord., 2009, 115, 386–394 http://dx.doi.org/10.1016/j.jad.2008.10.00610.1016/j.jad.2008.10.006Search in Google Scholar

[91] Jin X., Wu X., Wang J., Huang B., Wang Q., Zhang T., et al., [Effect of transcranial magnetic stimulation on rehabilitation of motor function in patients with cerebral infarction], Zhonghua Yi Xue Za Zhi, 2002, 82, 534–537 Search in Google Scholar

[92] Akamatsu N., Fueta Y., Endo Y., Matsunaga K., Uozumi T., Tsuji S., Decreased susceptibility to pentylenetetrazol-induced seizures after low-frequency transcranial magnetic stimulation in rats, Neurosci. Lett., 2001, 310, 153–156 http://dx.doi.org/10.1016/S0304-3940(01)02116-410.1016/S0304-3940(01)02116-4Search in Google Scholar

[93] Macdonell R.A., King M.A., Newton M.R., Curatolo J.M., Reutens D.C., Berkovic S.F., Prolonged cortical silent period after transcranial magnetic stimulation in generalized epilepsy, Neurology 2001, 57, 706–708 http://dx.doi.org/10.1212/WNL.57.4.70610.1212/WNL.57.4.706Search in Google Scholar

[94] Cincotta M., Borgheresi A., Boffi P., Vigliano P., Ragazzoni A., Zaccara G., et al., Bilateral motor cortex output with intended unimanual contraction in congenital mirror movements, Neurology, 2002, 58, 1290–1293 http://dx.doi.org/10.1212/WNL.58.8.129010.1212/WNL.58.8.1290Search in Google Scholar

[95] Ertas N.K., Gul G., Altunhalka A., Kirbas D., Cortical silent period following transcranial magnetic stimulation in epileptic patients, Epileptic Disord., 2000, 2, 137–140 Search in Google Scholar

[96] Groppa S., Siebner H.R., Kurth C., Stephani U., Siniatchkin M., Abnormal response of motor cortex to photic stimulation in idiopathic generalized epilepsy, Epilepsia, 2008, 49, 2022–2029 http://dx.doi.org/10.1111/j.1528-1167.2008.01709.x10.1111/j.1528-1167.2008.01709.xSearch in Google Scholar

[97] Nezu A., Kimura S., Ohtsuki N., Tanaka M., Transcranial magnetic stimulation in benign childhood epilepsy with centro-temporal spikes, Brain Dev., 1997, 19, 134–137 http://dx.doi.org/10.1016/S0387-7604(96)00497-410.1016/S0387-7604(96)00497-4Search in Google Scholar

[98] Michelucci R., Passarelli D., Riguzzi P., Buzzi A.M., Gardella E., Tassinari C.A., Transcranial magnetic stimulation in partial epilepsy: druginduced changes of motor excitability, Acta Neurol. Scand., 1996, 94, 24–30 http://dx.doi.org/10.1111/j.1600-0404.1996.tb00034.x10.1111/j.1600-0404.1996.tb00034.xSearch in Google Scholar PubMed

[99] Cantello R., Civardi C., Cavalli A., Varrasi C., Tarletti R., Monaco F., et al., Cortical excitability in cryptogenic localization-related epilepsy: interictal transcranial magnetic stimulation studies, Epilepsia, 2000, 41, 694–704 http://dx.doi.org/10.1111/j.1528-1157.2000.tb00230.x10.1111/j.1528-1157.2000.tb00230.xSearch in Google Scholar PubMed

[100] Badawy R.A., Macdonell R.A., Berkovic S.F., Newton M.R., Jackson G.D., Predicting seizure control: cortical excitability and antiepileptic medication, Ann. Neurol., 2010, 67, 64–73 http://dx.doi.org/10.1002/ana.2180610.1002/ana.21806Search in Google Scholar PubMed

[101] Cantello R., Varrasi C., Tarletti R., Cecchin M., D’Andrea F., Veggiotti P., et al., Ketogenic diet: electrophysiological effects on the normal human cortex, Epilepsia, 2007, 48, 1756–1763 http://dx.doi.org/10.1111/j.1528-1167.2007.01156.x10.1111/j.1528-1167.2007.01156.xSearch in Google Scholar PubMed

[102] Rotenberg A., Bae E.H., Muller P.A., Riviello J.J.Jr., Bourgeois B.F., et al., In-session seizures during low-frequency repetitive transcranial magnetic stimulation in patients with epilepsy, Epilepsy Behav., 2009, 16, 353–355 http://dx.doi.org/10.1016/j.yebeh.2009.08.01010.1016/j.yebeh.2009.08.010Search in Google Scholar PubMed PubMed Central

[103] Fregni F., Marcolin M.A., Myczkowski M., Amiaz R., Hasey G., Rumi D.O., et al., Predictors of antidepressant response in clinical trials of transcranial magnetic stimulation, Int. J. Neuropsychopharmacol., 2006, 9, 641–654 http://dx.doi.org/10.1017/S146114570500628010.1017/S1461145705006280Search in Google Scholar PubMed

[104] Hsu W.Y., Cheng C.H., Lin M.W., Shih Y.H., Liao K.K., Lin Y.Y., Antiepileptic effects of low frequency repetitive transcranial magnetic stimulation: a meta-analysis, Epilepsy Res., 2011, 96, 231–240 http://dx.doi.org/10.1016/j.eplepsyres.2011.06.00210.1016/j.eplepsyres.2011.06.002Search in Google Scholar PubMed

[105] Lewinsohn P.M., Hops H., Roberts R.E., Seeley J.R., Andrews J.A., Adolescent psychopathology: I. Prevalence and incidence of depression and other DSM-III-R disorders in high school students, J. Abnorm. Psychol., 1993, 102, 133–144 http://dx.doi.org/10.1037/0021-843X.102.1.13310.1037/0021-843X.102.1.133Search in Google Scholar

[106] Birmaher B., Ryan N.D., Williamson D.E., Brent D.A., Kaufman J., Dahl R.E., et al., Childhood and adolescent depression: a review of the past 10 years. Part I., J. Am. Acad. Child Adolesc. Psychiatry, 1996, 35, 1427–1439 http://dx.doi.org/10.1097/00004583-199611000-0001110.1097/00004583-199611000-00011Search in Google Scholar PubMed

[107] Birmaher B., Ryan N.D., Williamson D.E., Brent D.A., Kaufman J., Childhood and adolescent depression: a review of the past 10 years. Part II., J. Am. Acad. Child Adolesc. Psychiatry, 1996, 35, 1575–1583 http://dx.doi.org/10.1097/00004583-199612000-0000810.1097/00004583-199612000-00008Search in Google Scholar PubMed

[108] Carvalho A.F., Cavalcante J.L., Castelo M.S., Lima M.C., Augmentation strategies for treatment-resistant depression: a literature review, J. Clin. Pharm. Ther., 2007, 32, 415–428 http://dx.doi.org/10.1111/j.1365-2710.2007.00846.x10.1111/j.1365-2710.2007.00846.xSearch in Google Scholar

[109] George M.S., Transcranial magnetic stimulation for the treatment of depression, Expert Rev. Neurother., 2010, 10, 1761–1772 http://dx.doi.org/10.1586/ern.10.9510.1586/ern.10.95Search in Google Scholar

[110] Garcia K.S., Flynn P., Pierce K.J., Caudle M., Repetitive transcranial magnetic stimulation treats postpartum depression, Brain Stimul., 2010, 3, 36–41 http://dx.doi.org/10.1016/j.brs.2009.06.00110.1016/j.brs.2009.06.001Search in Google Scholar

[111] Figiel G.S., Epstein C., McDonald W.M., Amazon-Leece J., Figiel L., Saldivia A., et al., The use of rapid-rate transcranial magnetic stimulation (rTMS) in refractory depressed patients, J. Neuropsychiatry Clin. Neurosci., 1998, 10, 20–25 10.1176/jnp.10.1.20Search in Google Scholar

[112] Fregni F., Marcolin M.A., Myczkowski M., Amiaz R., Hasey G., Rumi D.O., et al., Predictors of antidepressant response in clinical trials of transcranial magnetic stimulation, Int. J. Neuropsychopharmacol., 2006, 9, 641–654 http://dx.doi.org/10.1017/S146114570500628010.1017/S1461145705006280Search in Google Scholar

[113] Mayer G., Faivel N., Aviram S., Walter G., Bloch Y., Repetitive transcranial magnetic stimulation in depressed adolescents: experience, knowledge, and attitudes of recipients and their parents, J. ECT, 2012, 28, 104–107 10.1097/YCT.0b013e318250058cSearch in Google Scholar

[114] Gilbert D.L., Isaacs K.M., Augusta M., Macneil L.K., Mostofsky S.H., Motor cortex inhibition: a marker of ADHD behavior and motor development in children, Neurology, 2011, 76, 615–621 http://dx.doi.org/10.1212/WNL.0b013e31820c2ebd10.1212/WNL.0b013e31820c2ebdSearch in Google Scholar

[115] Winterer G., Weinberger D.R., Genes, dopamine and cortical signalto-noise ratio in schizophrenia, Trends Neurosci., 2004, 27, 683–690 http://dx.doi.org/10.1016/j.tins.2004.08.00210.1016/j.tins.2004.08.002Search in Google Scholar

[116] Buchmann J., Wolters A., Haessler F., Bohne S., Nordbeck R., Kunesch E., Disturbed transcallosally mediated motor inhibition in children with attention deficit hyperactivity disorder (ADHD), Clin. Neurophysiol., 2003, 114, 2036–2042 http://dx.doi.org/10.1016/S1388-2457(03)00208-610.1016/S1388-2457(03)00208-6Search in Google Scholar

[117] Garvey M.A., Barker C.A., Bartko J.J., Denckla M.B., Wassermann E.M., Castellanos F.X., et al., The ipsilateral silent period in boys with attention-deficit/hyperactivity disorder, Clin. Neurophysiol., 2005, 116, 1889–1896 http://dx.doi.org/10.1016/j.clinph.2005.03.01810.1016/j.clinph.2005.03.018Search in Google Scholar PubMed

[118] Buchmann J., Gierow W., Weber S., Hoeppner J., Klauer T., Benecke R., et al., Restoration of disturbed intracortical motor inhibition and facilitation in attention deficit hyperactivity disorder children by methylphenidate, Biol. Psychiatry, 2007, 62, 963–969 http://dx.doi.org/10.1016/j.biopsych.2007.05.01010.1016/j.biopsych.2007.05.010Search in Google Scholar

[119] Weaver L., Rostain A.L., Mace W., Akhtar U., Moss E., O’Reardon J.P., Transcranial magnetic stimulation (TMS) in the treatment of attention-deficit/hyperactivity disorder in adolescents and young adults: a pilot study, J. ECT, 2012, 28, 98–103 10.1097/YCT.0b013e31824532c8Search in Google Scholar

[120] Bloch Y., Harel E.V., Aviram S., Govezensky J., Ratzoni G., Levkovitz Y., Positive effects of repetitive transcranial magnetic stimulation on attention in ADHD Subjects: a randomized controlled pilot study, World J. Biol. Psychiatry, 2010, 11, 755–758 http://dx.doi.org/10.3109/15622975.2010.48446610.3109/15622975.2010.484466Search in Google Scholar

[121] Moll G.H., Wischer S., Heinrich H., Tergau F., Paulus W., Rothenberger A., Deficient motor control in children with tic disorder: evidence from transcranial magnetic stimulation, Neurosci. Lett., 1999, 272, 37–40 http://dx.doi.org/10.1016/S0304-3940(99)00575-310.1016/S0304-3940(99)00575-3Search in Google Scholar

[122] Gilbert D.L., Bansal A.S., Sethuraman G., Sallee F.R., Zhang J., Lipps T., et al., Association of cortical disinhibition with tic, ADHD, and OCD severity in Tourette syndrome, Mov. Disord., 2004, 19, 416–425 http://dx.doi.org/10.1002/mds.2004410.1002/mds.20044Search in Google Scholar PubMed

[123] Paes F., Machado S., Arias-Carrión O., Velasques B., Teixeira S., Cagy M., et al., The value of repetitive transcranial magnetic stimulation (rTMS) for the treatment of anxiety disorders: an integrative review, CNS Neurol. Disord. Drug Targets, 2011, 10, 610–620 http://dx.doi.org/10.2174/18715271179623494310.2174/187152711796234943Search in Google Scholar PubMed

[124] Blom R.M., Figee M., Vulink N., Denys D., Update on repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: different targets, Curr. Psychiatry Rep., 2011, 13, 289–294 http://dx.doi.org/10.1007/s11920-011-0205-310.1007/s11920-011-0205-3Search in Google Scholar PubMed PubMed Central

[125] Dlabac-de Lange J.J., Knegtering R., Aleman A., Repetitive transcranial magnetic stimulation for negative symptoms of schizophrenia: review and meta-analysis, J. Clin. Psychiatry, 2010, 71, 411–418 http://dx.doi.org/10.4088/JCP.08r04808yel10.4088/JCP.08r04808yelSearch in Google Scholar PubMed

[126] Walter G., Tormos J.M., Israel J.A., Pascual-Leone A., Transcranial magnetic stimulation in young persons: a review of known cases, J. Child Adolesc. Psychopharmacol., 2001, 11, 69–75 http://dx.doi.org/10.1089/10445460175014348310.1089/104454601750143483Search in Google Scholar PubMed

[127] Fitzgerald P.B., Benitez J., Daskalakis J.Z., De C.A., Kulkarni J., The treatment of recurring auditory hallucinations in schizophrenia with rTMS, World J. Biol. Psychiatry, 2006, 7, 119–122 http://dx.doi.org/10.1080/1562297050047470510.1080/15622970500474705Search in Google Scholar PubMed

[128] Zernikow B., Wager J., Hechler T., Hasan C., Rohr U., Dobe M., et al., Characteristics of highly impaired children with severe chronic pain: a 5-year retrospective study on 2249 pediatric pain patients, BMC Pediatr., 2012, 12, 54 http://dx.doi.org/10.1186/1471-2431-12-5410.1186/1471-2431-12-54Search in Google Scholar

[129] Brigo F., Storti M., Nardone R., Fiaschi A., Bongiovanni L.G., Tezzon F., et al., Transcranial magnetic stimulation of visual cortex in migraine patients: a systematic review with meta-analysis, J. Headache Pain, 2012, 13, 339–349 http://dx.doi.org/10.1007/s10194-012-0445-610.1007/s10194-012-0445-6Search in Google Scholar

[130] Siniatchkin M., Reich A.L., Shepherd A.J., van Baalen A, Siebner H.R., Stephani U., Peri-ictal changes of cortical excitability in children suffering from migraine without aura, Pain, 2009, 147, 132–140 http://dx.doi.org/10.1016/j.pain.2009.08.02810.1016/j.pain.2009.08.028Search in Google Scholar

[131] Lipton R.B., Dodick D.W., Silberstein S.D., Saper J.R., Aurora S.K., Pearlman S.H., et al., Single-pulse transcranial magnetic stimulation for acute treatment of migraine with aura: a randomised, doubleblind, parallel-group, sham-controlled trial, Lancet Neurol., 2010, 9, 373–380 http://dx.doi.org/10.1016/S1474-4422(10)70054-510.1016/S1474-4422(10)70054-5Search in Google Scholar

[132] Barlow K.M., Crawford S., Stevenson A., Sandhu S.S., Belanger F., Dewey D., Epidemiology of postconcussion syndrome in pediatric mild traumatic brain injury, Pediatrics, 2010, 126, e374–e381 http://dx.doi.org/10.1542/peds.2009-092510.1542/peds.2009-0925Search in Google Scholar PubMed

[133] Demirtas-Tatlidede A., Vahabzadeh-Hagh A.M., Bernabeu M., Tormos J.M., Pascual-Leone A., Noninvasive brain stimulation in traumatic brain injury, J. Head Trauma Rehabil., 2012, 27, 274–292 http://dx.doi.org/10.1097/HTR.0b013e318217df5510.1097/HTR.0b013e318217df55Search in Google Scholar PubMed PubMed Central

[134] Tremblay S., De B.L., Lassonde M., Théoret H., Evidence for the specificity of intracortical inhibitory dysfunction in asymptomatic concussed athletes, J. Neurotrauma, 2011, 28, 493–502 http://dx.doi.org/10.1089/neu.2010.161510.1089/neu.2010.1615Search in Google Scholar PubMed

[135] Livingston S.C., Goodkin H.P., Hertel J.N., Saliba E.N., Barth J.T., Ingersoll C.D., Differential rates of recovery after acute sport-related concussion: electrophysiologic, symptomatic, and neurocognitive indices, J. Clin. Neurophysiol., 2012, 29, 23–32 http://dx.doi.org/10.1097/WNP.0b013e318246ae4610.1097/WNP.0b013e318246ae46Search in Google Scholar PubMed

[136] Villamar M.F., Santos P.A., Fregni F., Zafonte R., Noninvasive brain stimulation to modulate neuroplasticity in traumatic brain injury, Neuromodulation, 2012, 15, 326–338 http://dx.doi.org/10.1111/j.1525-1403.2012.00474.x10.1111/j.1525-1403.2012.00474.xSearch in Google Scholar PubMed

[137] Bernabeu M., Demirtas-Tatlidede A., Opisso E., Lopez R., Tormos J.M., Pascual-Leone A., Abnormal corticospinal excitability in traumatic diffuse axonal brain injury, J. Neurotrauma, 2009, 26, 2185–2193 http://dx.doi.org/10.1089/neu.2008.085910.1089/neu.2008.0859Search in Google Scholar PubMed PubMed Central

[138] Dobson C.B., Villagra F., Clowry G.J., Smith M., Kenwrick S., Donnai D., et al., Abnormal corticospinal function but normal axonal guidance in human L1CAM mutations, Brain, 2001, 124, 2393–2406 http://dx.doi.org/10.1093/brain/124.12.239310.1093/brain/124.12.2393Search in Google Scholar

[139] Nezu A., Kimura S., Takeshita S., Tanaka M., Characteristic response to transcranial magnetic stimulation in Rett syndrome, Electroencephalogr. Clin. Neurophysiol., 1998, 109, 100–103 http://dx.doi.org/10.1016/S0924-980X(97)00081-710.1016/S0924-980X(97)00081-7Search in Google Scholar

[140] Nardone R., Bergmann J., Lochner P., Caleri F., Kunz A., Staffen W., et al., Modafinil reverses hypoexcitability of the motor cortex in narcoleptic patients: a TMS study, Sleep Med., 2010, 11, 870–875 http://dx.doi.org/10.1016/j.sleep.2010.05.00710.1016/j.sleep.2010.05.007Search in Google Scholar PubMed

[141] Wu S.W., Shahana N., Huddleston D.A., Lewis A.N., Gilbert D.L., Safety and tolerability of theta-burst transcranial magnetic stimulation in children, Dev. Med. Child Neurol., 2012, 54, 636–639 http://dx.doi.org/10.1111/j.1469-8749.2012.04300.x10.1111/j.1469-8749.2012.04300.xSearch in Google Scholar PubMed

[142] Wray C.D., Blakely T.M., Poliachik S.L., Poliakov A., McDaniel S.S., Novotny E.J., et al., Multimodality localization of the sensorimotor cortex in pediatric patients undergoing epilepsy surgery, J. Neurosurg. Pediatr., 2012, 10, 1–6 http://dx.doi.org/10.3171/2012.3.PEDS1155410.3171/2012.3.PEDS11554Search in Google Scholar PubMed PubMed Central

[143] Coburger J., Karhu J., Bittl M., Hopf N.J., First preoperative functional mapping via navigated transcranial magnetic stimulation in a 3-yearold boy, J. Neurosurg. Pediatr., 2012, 9, 660–664 http://dx.doi.org/10.3171/2012.2.PEDS1142610.3171/2012.2.PEDS11426Search in Google Scholar PubMed

[144] Juenger H., Ressel V., Braun C., Ernemann U., Schuhmann M., Krägeloh-Mann I., et al., Misleading functional magnetic resonance imaging mapping of the cortical hand representation in a 4-yearold boy with an arteriovenous malformation of the central region, J. Neurosurg. Pediatr., 2009, 4, 333–338 http://dx.doi.org/10.3171/2009.5.PEDS0846610.3171/2009.5.PEDS08466Search in Google Scholar PubMed

[145] Forster M.T., Hattingen E., Senft C., Gasser T., Seifert V., Szelenyi A., Navigated transcranial magnetic stimulation and functional magnetic resonance imaging: advanced adjuncts in preoperative planning for central region tumors, Neurosurgery, 2011, 68, 1317–1324 10.1227/NEU.0b013e31820b528cSearch in Google Scholar PubMed

[146] Auvichayapat N., Rotenberg A., Gersner R., et al., Transcranial direct current stimulation for treatment of refractory childhood focal epilepsy, Brain Stimul., 2013, doi: 10.1016/j.brs.2013.01.0009 [Epub ahead of print] Search in Google Scholar

[147] Varga E.T., Terney D., Atkins M.D., Nikanorova M., Jeppesen D.S., Uldall P., et al., Transcranial direct current stimulation in refractory continuous spikes and waves during slow sleep: a controlled study, Epilepsy Res., 2011, 97, 142–145 http://dx.doi.org/10.1016/j.eplepsyres.2011.07.01610.1016/j.eplepsyres.2011.07.016Search in Google Scholar PubMed

[148] Young S.J., Bertucco M., Sheehan-Stross R., Sanger T.D., Cathodal transcranial direct current stimulation in children with dystonia a pilot open-label trial, J. Child Neurol., 2012, doi:10.1177/0883073812460092 [Epub ahead of print] 10.1177/0883073812460092Search in Google Scholar PubMed

[149] Pinchuk D., Pinchuk O., Sirbiladze K., Shugar O., Clinical effectiveness of primary and secondary headache treatment by transcranial direct current stimulation, Front. Neurol., 2013, 4, 25 http://dx.doi.org/10.3389/fneur.2013.0002510.3389/fneur.2013.00025Search in Google Scholar PubMed PubMed Central

[150] Osborne L., Savant for a day, NY Times Magazine, 2003, June 22 Search in Google Scholar

[151] Illes J., Gallo M., Kirschen M.P., An ethics perspective on transcranial magnetic stimulation (TMS) and human neuromodulation, Behav. Neurol., 2006, 17, 149–157 10.1155/2006/791072Search in Google Scholar PubMed PubMed Central

[152] Cohen K.R., Levy N., O’Shea J., Shea N., Savulescu J., The neuroethics of non-invasive brain stimulation, Curr. Biol., 2012, 22, R108–R111 http://dx.doi.org/10.1016/j.cub.2012.01.01310.1016/j.cub.2012.01.013Search in Google Scholar PubMed PubMed Central

[153] McKinley R.A., Bridges N., Walters C.M., Nelson J., Modulating the brain at work using noninvasive transcranial stimulation, Neuroimage, 2012, 59, 129–137 http://dx.doi.org/10.1016/j.neuroimage.2011.07.07510.1016/j.neuroimage.2011.07.075Search in Google Scholar PubMed

Published Online: 2013-6-9
Published in Print: 2013-6-1

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