Abstract
A hiccup is a sudden contraction of the inspiratory and diaphragmatic muscles followed by an abrupt closure of the glottis; that produces a characteristic noise resulting from vibrations of the vocal cords. Brief episodes of hiccups are common in humans at all stages of life and are usually benign. Prolonged attacks that last for days or weeks are considered a more serious phenomenon and may indicate an underlying disorder warranting a comprehensive medical evaluation. These attacks have been associated with significant burden and morbidity. The most common triggers for acute hiccups are linked with gastro-intestinal causes, such as the gastric distension that occurs after an abundant meal, or with gastroesophageal disease. Sudden changes in temperature, excessive alcohol consumption, as well as excitement or emotional stress, may also set off acute hiccups. Certain drugs, including benzodiazepines, barbiturates, and many others, have been reported to induce hiccups. Drug-induced hiccups are diagnosed by exclusion of other causes and represent a very unusual side-effect of drugs like corticosteroids. We present a case of hiccups associated with intra-articular Diprospan (Betamethasone Sodium Phosphate) administration.
[1] Bizec JL., Launois S., Bolgert F., Lamas G., Chollet R., Derenne JP., Hiccups in adults, Rev. Mal Respir., 1995,12, 219–229 Search in Google Scholar
[2] Liaw CC., Wang CH., Chang HK., Wang HM., Huang JS., Lin YC., et al., Cisplatin-related hiccups: male predominance, induction by dexamethasone, and protection against nausea and vomiting, J. Pain Symptom Manage, 2005, 30,359–366 http://dx.doi.org/10.1016/j.jpainsymman.2005.08.00810.1016/j.jpainsymman.2005.08.008Search in Google Scholar
[3] Bagheri H., Cismondo S., Montastruc JL., Drug-induced hiccup: a review of the France pharmacologic vigilance database, Therapie, 1999, 54, 35–39 Search in Google Scholar
[4] Federspil PA, Zenk J. Hiccup. HNO, 1999, 47,867–875 http://dx.doi.org/10.1007/s00106005052710.1007/s001060050527Search in Google Scholar
[5] Javot L., Scala-Bertola J., Petitpain N., Trechot P., Pere P., Gillet P., Methotrexate-induced hiccups, Rheumatology (Oxford), 2011, 50,989–990 http://dx.doi.org/10.1093/rheumatology/keq43810.1093/rheumatology/keq438Search in Google Scholar
[6] Surendiran A., Krishna Kumar D., Adithan C., Azithromycin-induced hiccups, J. Postgrad. Med, 2008, 54,330–331 http://dx.doi.org/10.4103/0022-3859.4352110.4103/0022-3859.43521Search in Google Scholar
[7] Ross J., Eledrisi M., Casner P., Persistent hiccups induced by dexamethasone, West J. Med., 1999, 170,51–52 Search in Google Scholar
[8] Kolodzik PW., Eilers MA., Hiccups (singultus): review and approach to management, Ann. Emerg. Med., 1991, 20,565–573 http://dx.doi.org/10.1016/S0196-0644(05)81620-810.1016/S0196-0644(05)81620-8Search in Google Scholar
[9] Chuang-Chi Liaw, Cheng-Hsu Wang, Hsien-Kun Chang, Hung-Ming Wang, Jen-Sheng Huang, Yung-Chang Lin, et al., Cisplatin-Related Hiccups: Male Predominance, Induction by Dexamethasone, and Protection Against Nausea and Vomiting, J.Pain and symptom management, 2005, 30,359–366 http://dx.doi.org/10.1016/j.jpainsymman.2005.08.00810.1016/j.jpainsymman.2005.08.008Search in Google Scholar
[10] Cersosimo RJ., Brophy MT., Hiccups with high dose dexamethasone administration, Cancer, 1998, 82, 412–414 http://dx.doi.org/10.1002/(SICI)1097-0142(19980115)82:2<415::AID-CNCR23>3.0.CO;2-010.1002/(SICI)1097-0142(19980115)82:2<415::AID-CNCR23>3.0.CO;2-0Search in Google Scholar
[11] Lewis JH., Hiccups: causes and cures, J. Clin. Gastroenterol., 1985, 7,539–552 http://dx.doi.org/10.1097/00004836-198512000-0002110.1097/00004836-198512000-00021Search in Google Scholar
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