MCM-41-SO3H-catalyzed synthesis of highly substituted 3-amino-imidazo[1,2-a]pyridines or pyrazines via the Groebke-Blackburn-Bienaymé multicomponent reaction under grinding conditions at ambient temperature

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Abstract

Environmentally-friendly and highly efficient method has been developed by a sequential one-pot, three-component reaction between isocyanides, aldehydes and 2-aminopyridines or 2 aminopyrazines under solvent-free and grinding- conditions at room temperature in the presence of nano-ordered MCM-41-SO3H.

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Scientia Iranica
Volume 23, Issue 6 - Serial Number 6
Transactions on Chemistry (C)
December 2016
Pages 2724-2734

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