REVIEW   

Minerva Dental and Oral Science 2022 June;71(3):192-8

DOI: 10.23736/S2724-6329.21.04637-4

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Advancements in diagnostic techniques for oral cancer detection

Gunjan KUMAR ¹, Samikshya JENA ¹ ✉, Avinash JNANESWAR ¹, Kunal JHA ¹, Vinay SURESAN ¹, Arpita SINGH ²

¹ Department of Public Health Dentistry, Kalinga Institute of Dental Science, KIIT Deemed to be University, Bhubaneswar, India; ² KIIT Deemed to be University, Bhubaneswar, India

Oral malignancy is among the highest prevalent malignancies all over the world. In comparison to systemic malignancies such as lung cancer and colon cancer, they are frequently overlooked by the general public. Nevertheless, they can be exceedingly lethal if left ignored, regardless at the early stage of the condition. Dentists are the finest qualified healthcare specialists in this sector and are responsible for detecting benign and potentially malignant oral conditions such as oral cancers. Oral carcinoma’s high prevalence and delayed appearance are serious international medical concerns. Early detection and management of oral carcinoma are the key goals of the World Health Organization (WHO). The identification of key clinical manifestations during the preliminary oral examination can enhance the patient’s likelihood of living. Unfortunately, the conventional technology’s practical value is limited by a number of drawbacks. Current advancements in optical scanning techniques, such as tissue-fluorescence imaging and optical coherence tomography, have proven to be quite effective. In particular, nanoparticle-based immunosensors, genomics, and salivary biomarkers, epigenetics and microarray have all received a lot of attention. Raising awareness about frequent dental examinations and using noninvasive, effective, and cost-effective screening tools would improve initial stage detection of oral carcinoma and improve patients’ longevity.

KEY WORDS: Neoplasms; Diagnostic techniques and procedures; Early diagnosis