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ORIGINAL ARTICLE EPIDEMIOLOGY AND CLINICAL MEDICINE
The Journal of Sports Medicine and Physical Fitness 2022 November;62(11):1526-33
DOI: 10.23736/S0022-4707.21.13234-7
Copyright © 2021 EDIZIONI MINERVA MEDICA
language: English
Association between cardiorespiratory fitness and metabolic health in overweight and obese adults
Eero A. HAAPALA 1, 2 ✉, Tanja SJÖROS 3, Saara LAINE 3, Taru GARTHWAITE 3, Petri KALLIO 4, Maria SAARENHOVI 4, Henri VÄHÄ-YPYÄ 5, Eliisa LÖYTTYNIEMI 6, Harri SIEVÄNEN 5, Noora HOUTTU 7, Kirsi LAITINEN 7, Kari KALLIOKOSKI 3, Juhani KNUUTI 3, Tommi VASANKARI 4, 8, Ilkka H. HEINONEN 3, 9
1 Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland; 2 School of Medicine, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland; 3 Turku PET Center, Turku University Hospital, University of Turku, Turku, Finland; 4 Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, University of Turku, Turku, Finland; 5 The UKK Institute for Health Promotion Research, Tampere, Finland; 6 Department of Biostatistics, University of Turku, Turku, Finland; 7 Institute of Biomedicine, University of Turku, Turku, Finland; 8 Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; 9 Rydberg Laboratory of Applied Sciences, University of Halmstad, Halmstad, Sweden
BACKGROUND: Cardiorespiratory fitness (CRF) has been inversely associated with insulin resistance and clustering of cardiometabolic risk factors among overweight and obese individuals. However, most previous studies have scaled CRF by body mass (BM) possibly inflating the association between CRF and cardiometabolic health. We investigated the associations of peak oxygen uptake (V̇O
METHODS: V̇O
RESULTS: V̇O
CONCLUSIONS: Our results suggest that using BM-1 as a scaling factor confounds the associations between CRF and cardiometabolic risk in overweight/obese adults with the metabolic syndrome.
KEY WORDS: Physical fitness; Metabolic syndrome; Insulin resistance