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Intracystic papilloma in the breast of a male given long-term phenothiazine therapy: A case report

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Abstract

We experienced a very rare case of intracystic papilloma in a 57-year-old man who came to our hospital complaining of a left subareolar mass and nipple discharge. The patient had a history of chronic schizophrenia, necessitating long-term treatment with phenothiazines. His serum prolactin levels were elevated. Mammography demonstrated a well defined mass with microcalcifications. Ultrasonography revealed a cyst with an intracystic component. The inner lesion of the mass enhanced on contrast-enhanced computed tomography. The carcinoembryonic antigen concentration of the cyst fluid was 400 ng/mL and no malignant cells were found by aspiration biopsy cytology. Excisional biopsy was performed under local anesthesia. Pathological examination revealed the intracystic component to be intracystic papilloma . There are ten reports of male intracystic papilloma including ours. We report the second case of a patient given long-term phenothiazine therapy, which is known to increase serum prolactin levels.

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Authors and Affiliations

  1. Department of Surgery, Minoh City Hospital, 5-7-1, Kayano, Minon, 562-8562, Osaka, Japan

    Hitoshi Yamamoto, Rio Handa, Yasuto Naoi, Satoshi Oshima, Takeshi Koto, Masaki Tsujie, Shohei lijima, Eiji Kurokawa & Nobuteru Kikkawa

  2. Department of Pathology, Osaka Medical College, Japan

    Yoshikazu Okada

  3. Department of Clinical Pathology, Minoh City Hospital, Japan

    Haruo Taniguchi

  4. Neurosanatorium Minoh, Japan

    Kensuke Kadone

Authors
  1. Hitoshi Yamamoto
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  2. Yoshikazu Okada
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  3. Haruo Taniguchi
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  4. Rio Handa
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  5. Yasuto Naoi
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  6. Satoshi Oshima
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  7. Takeshi Koto
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  8. Masaki Tsujie
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  9. Shohei lijima
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  10. Eiji Kurokawa
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  12. Kensuke Kadone
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Yamamoto, H., Okada, Y., Taniguchi, H. et al. Intracystic papilloma in the breast of a male given long-term phenothiazine therapy: A case report. Breast Cancer 13, 84–88 (2006). https://doi.org/10.2325/jbcs.13.84

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  • DOI: https://doi.org/10.2325/jbcs.13.84

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