doiSerbia

Comparative screening of the anti-oxidant and antimicrobial activities of Sempervivum marmoreum L. extracts obtained by various extraction techniques

Stojičević Saša S. (Tehnološki fakultet, Leskovac)
Stanisavljević Ivana T. (Tehnološki fakultet, Leskovac)
Veličković Dragan T. (Zdravlje-Actavis, Leskovac)
Veljković Vlada B. (Tehnološki fakultet, Leskovac)
Lazić Miodrag L. (Tehnološki fakultet, Leskovac)

This paper presents a comparative study of the anti-oxidant and anti-microbial activities, total phenolic compounds and total flavonoids in extracts obtained from houseleek (Sempervivum marmoreum L.) leaves by the classical (maceration), ultrasonic and Soxhlet extraction (CE, UE and SE, respectively). The extract obtained by the CE contained higher amounts of phenolic and flavonoid compounds and showed a better antioxidant activity than those obtained using other two techniques. All the extracts, independent of the extraction technique applied, showed antimicrobial activities against Aspergillus niger and Candida albicans only but not against the tested bacteria.

Keywords: antimicrobial activity, anti-oxidant activity, extraction, houseleek, Sempervivum marmoreum L., ultrasound