Archives of Biological Sciences 2010 Volume 62, Issue 1, Pages: 167-174
https://doi.org/10.2298/ABS1001167S
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In vitro synergistic antibacterial activity of Salvia officinalis L. and some preservatives
Stanojević Dragana 
(Institut za biologiju, Prirodno-matematički fakultet, Kragujevac)
Čomić Ljiljana (Institut za biologiju, Prirodno-matematički fakultet, Kragujevac)
Stefanović Olgica (Institut za biologiju, Prirodno-matematički fakultet, Kragujevac)
Solujić-Sukdolak Slavica (Institut za hemiju, Prirodno-matematički fakultet, Kragujevac)
The aim of this work was to investigate the antibacterial activity of aqueous extracts of the species Salvia officinalis L. and its synergistic action with the preservatives sodium nitrite, sodium benzoate and potassium sorbate in vitro against selected food spoiling bacteria. Synergism was assessed by the checkerboard assay method and quantitatively represented by the FIC index. Synergistic action was established for aqueous extract/sodium benzoate, aqueous extract/potassium sorbate, aqueous extract/sodium nitrite combinations. Synergism was detected in relation to: Agrobacterium tumefaciens, Bacillus subtilis and Proteus sp. Synergism was established at plant extract and preservative concentrations corresponding up to 1/8 MIC values.
Detected autoplagiarism. Link to the Editorial Decision 10.2298/ABS1004251U
Keywords: Salvia officinalis L., plant extracts, preservative, MIC, synergism